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公开(公告)号：EP4334394A1
公开(公告)日：2024-03-13
申请号：EP22799267.4
申请日：2022-04-07
发明人： SMITH, Bradley D. , LI, Dong-Hao
IPC分类号： C09B23/16 , G01N33/574 , C09B23/10
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公开(公告)号：EP4241663A1
公开(公告)日：2023-09-13
申请号：EP23187363.9
申请日：2019-04-05
IPC分类号： A61B5/00 , G01N21/47 , G01N21/25 , G01N21/359
摘要： A frequency domain diffuse optical spectroscopy (FD-DOS) device and calibration method. The FD-DOS device includes a radio frequency signal generator, a driver, a light source, a silicon photomultiplier, an analog to digital conversion circuit, and an electronic processing circuit. The light source is configured to generate modulated light at a plurality of different wavelengths and modulation frequencies. The silicon photomultiplier is configured to generate analog detection signals indicative of detected optical signals. The analog to digital conversion circuit is configured to generate digital sample values from the analog detection signals. The electronic processing circuit is configured to determine absorption values and scattering values based on the digital sample values. The electronic processing circuit is also configured to determine concentration values based on the absorption values and the scattering values. The electronic processing circuit is further configured to determine an image stream based on the concentration values.
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公开(公告)号：EP4171221A2
公开(公告)日：2023-05-03
申请号：EP21833830.9
申请日：2021-06-28
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公开(公告)号：EP4139402A1
公开(公告)日：2023-03-01
申请号：EP21792052.9
申请日：2021-02-22
发明人： SMITH, Bradley D. , LI, Donghao
IPC分类号： C09B23/02 , C09K11/06 , C07D209/10
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公开(公告)号：EP3695382A1
公开(公告)日：2020-08-19
申请号：EP18799616.0
申请日：2018-10-09
发明人： THIBAULT, Jean-Baptiste , SRIVASTAVA, Somesh , HSIEH, Jiang , BOUMAN, Charles A , YE, Dong , SAUER, Ken
IPC分类号： G06T11/00
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公开(公告)号：EP2970440B1
公开(公告)日：2019-11-20
申请号：EP14768752.9
申请日：2014-03-14
IPC分类号： C07K16/00 , C07K16/46 , A61K41/00 , G01N33/531
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7.发明公开
公开(公告)号：EP3516386A1
公开(公告)日：2019-07-31
申请号：EP17854139.7
申请日：2017-09-26
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公开(公告)号：EP3374371A1
公开(公告)日：2018-09-19
申请号：EP16864870.7
申请日：2016-11-08
IPC分类号： C07K1/14 , C07K16/28 , A61K39/395 , C07D209/16
CPC分类号： C07K1/22 , B01D15/3828 , B01D71/10 , B01J20/265 , B01J20/2805 , B01J20/288 , B01J20/321 , B01J20/3212 , B01J20/3217 , B01J20/3246 , C07D209/16 , C07K16/065 , C07K16/2887 , C07K2317/24
摘要： Disclosed are purification systems and methods for providing purified preparations of antibodies from a fluid, particularly a biological fluid comprising or suspected to contain antibody (e.g., blood, serum, plasma, ascites fluid). Reusable and stable synthetic purification columns comprising membranes of a suitable separation matrix material, such as a nylon membrane or regenerated cellulose membrane, having conjugated thereto a small molecule capture ligand, such as a short peptide or protein capable of acting as a ligand for a particular antibody of interest, such as a peptide having a sequence with binding affinity for a nucleotide binding site (NBS) of a selected antibody of interest, are also provided. Methods of preparing the purification columns are also disclosed. Methods for preparing high yield and high purity therapeutic antibody preparations, such as anti-cancer therapeutics, from a biological fluid, are also presented.
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公开(公告)号：EP3322509A1
公开(公告)日：2018-05-23
申请号：EP16825276.5
申请日：2016-07-15
发明人： MCGINN, Paul , ZOKOE, James
CPC分类号： F01N3/035 , B01D53/94 , B01D53/944 , B01D2255/202 , B01D2255/2022 , B01D2255/2065 , B01D2255/20715 , B01D2255/30 , B01D2255/407 , B01D2255/908 , B01D2255/915 , B01D2255/9155 , B01D2258/012 , B01J21/08 , B01J23/10 , B01J35/04 , B01J37/0219 , B01J37/0234 , B01J37/033 , B01J37/038 , B01J37/08 , B01J2523/00 , F01N3/0212 , F01N3/0222 , F01N3/0226 , F01N2330/06 , F01N2330/10 , F01N2330/12 , F01N2370/00 , F01N2510/065 , B01J2523/13 , B01J2523/3712 , B01J2523/41 , B01J2523/48 , B01J2523/23
摘要： A diesel soot filter includes a substrate having a surface disposed at least partially within a fluid path of the diesel soot filter. A glass catalyst is disposed on the surface of the substrate such that an exhaust gas contacts at least a portion of a surface of the glass catalyst as the exhaust gas moves within the diesel soot filter. The glass catalyst comprises a plurality of alkali metal ions disposed within the glass catalyst and releasable to the surface of the glass catalyst at a controlled rate and the alkali metal ions combust with the soot as the exhaust gas travels along the fluid path. An oxide basis of the glass catalyst comprises Silicon (Si), Potassium (K), Cesium (Ce), and Zirconium (Zr).
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10.发明公开IONIC LIQUID ELECTROLYTE AND METHOD TO ELECTRODEPOSIT METALS 审中-公开IONISCHERFLÜSSIGELEKTROLYTUND VERFAHREN ZUR ELEKTROPLATTIERUNG VON METALLEN
公开(公告)号：EP3132071A1
公开(公告)日：2017-02-22
申请号：EP15723342.0
申请日：2015-04-14
摘要： An electrolyte and a method to electroplate a metal on a substrate using the electrolyte are described. The electrolyte includes an imidazolium compound, a metal salt, and water. The imidazolium compound has formula (I) wherein R1, R2, R3, R4, and R5 are each independently selected from an H atom and an organic radical. L− is a compatible anion. The metal salt can include but is not limited to salts of the metals Li, Mg, Ca, Cr, Mn, Fe, Co, Ni, Cu, Zn, Cd, Pb, Bi, La, Ce, Al, Ag, Au, Ga, V, In, Nb, Mo, and W.
摘要翻译： 描述了电解质和使用电解质在基片上电镀金属的方法。 电解质包括咪唑鎓化合物，金属盐和水。 咪唑鎓化合物具有式（I），其中R 1，R 2，R 3，R 4和R 5各自独立地选自H原子和有机基团。 L-是相容的阴离子。 金属盐可以包括但不限于金属Li，Mg，Ca，Cr，Mn，Fe，Co，Ni，Cu，Zn，Cd，Pb，Bi，La，Ce，Al，Ag，Au， Ga，V，In，Nb，Mo和W.
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