公开(公告)号：EP2870151A2

公开(公告)日：2015-05-13

申请号：EP13816292.0

申请日：2013-07-08

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Ramakrishna Reddy, Matta ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  RAMAKRISHNA REDDY, Matta ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D413/10

CPC分类号： C07D413/14 ,  C07B2200/13

摘要： The present invention provides a novel crystalline Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides a novel crystalline Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it.

摘要翻译： 本发明提供了一种新型的唑来硫酸结晶形式，其制备方法和包含它的药物组合物。 本发明还提供了一种新型的吖唑烷酮莫昔米尔钾的结晶形式，其制备方法和包含它的药物组合物。

公开(公告)号：EP2852574A2

公开(公告)日：2015-04-01

申请号：EP13793172.1

申请日：2013-05-21

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Srinivasa Rao, Thungathurthy ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  SRINIVASA RAO, Thungathurthy ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D213/78

CPC分类号： C07D213/81

摘要： The present invention provides a novel process for the preparation of sorafenib tosylate polymorph III.

摘要翻译： 本发明提供了一种制备索拉非尼甲苯磺酸盐多晶型物III的新方法。

公开(公告)号：EP2938625A2

公开(公告)日：2015-11-04

申请号：EP13869498.9

申请日：2013-12-30

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Srinivasa Reddy, Katham ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  SRINIVASA REDDY, Katham ,  VAMSI KRISHNA, Bandi

IPC分类号： C07J43/00

CPC分类号： C07J43/003 ,  C07J1/0011 ,  C07J31/006

摘要： The present invention provides a novel process for the preparation of abiraterone. The present invention also provides a novel process for the preparation of abiraterone acetate.

公开(公告)号：EP2870151A4

公开(公告)日：2016-03-23

申请号：EP13816292

申请日：2013-07-08

申请人： HETERO RESEARCH FOUNDATION ,  PARTHASARADHI REDDY BANDI ,  RATHNAKAR REDDY KURA ,  MURALIDHARA REDDY DASARI ,  RAMAKRISHNA REDDY MATTA ,  VAMSI KRISHNA BANDI

发明人： PARTHASARADHI REDDY BANDI ,  RATHNAKAR REDDY KURA ,  MURALIDHARA REDDY DASARI ,  RAMAKRISHNA REDDY MATTA ,  VAMSI KRISHNA BANDI

IPC分类号： C07D413/10

CPC分类号： C07D413/14 ,  C07B2200/13

公开(公告)号：EP2981532A2

公开(公告)日：2016-02-10

申请号：EP14785011.9

申请日：2014-04-01

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Ramakrishna Reddy, Matta ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  RAMAKRISHNA REDDY, Matta ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D401/04 ,  C07D307/89 ,  A61K31/445

CPC分类号： C07D401/04 ,  C07B2200/13

摘要： The present invention provides a novel process for the preparation of pomalidomide crystalline Form I. The present invention also provides a process for the purification of pomalidomide.

摘要翻译： 本发明提供了一种制备泊马度胺晶型I的新方法。本发明还提供了一种用于纯化泊马度胺的方法。

公开(公告)号：EP3008047A2

公开(公告)日：2016-04-20

申请号：EP14810740.2

申请日：2014-06-12

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Venkat Narsimha Reddy, Adulla ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  VENKAT NARSIMHA REDDY, Adulla ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D305/00

CPC分类号： C07D305/14

摘要： The present invention provides an improved process for the preparation of 4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,13α-dihydroxy-7β,10β-dimethoxy-9-oxo-11-taxene (7β,10β-dimethoxy-10-deacetoxybaccatin III). The present invention also provides a novel process for the preparation of cabazitaxel.

摘要翻译： 本发明提供了制备4α-乙酰氧基-2α-苯甲酰氧基-5β，20-环氧-1β，13α-二羟基-7β，10β-二甲氧基-9-氧代-11-紫杉醇（7β，10β-二甲氧基 -10-脱乙酰氧基浆果赤霉素III）。 本发明还提供了一种制备卡巴他赛的新方法。

公开(公告)号：EP2925753A1

公开(公告)日：2015-10-07

申请号：EP13833875.1

申请日：2013-07-19

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Ramakrishna Reddy, Matta ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  RAMAKRISHNA REDDY, Matta ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D413/14

CPC分类号： C07D413/10 ,  A61K31/4245 ,  B01F3/0807 ,  B01F11/0028 ,  B01F15/00331 ,  B01F15/00389 ,  B01F15/00396 ,  B01F15/00538 ,  B01F15/026 ,  B01F2215/0073 ,  C07B2200/13 ,  C07D413/14 ,  C12M45/02 ,  G01N1/38

摘要： The present invention provides a novel amorphous Form of azilsartan acid, process for its preparation and pharmaceutical compositions comprising it. The present invention also provides novel crystalline Forms of azilsartan medoxomil, processes for their preparations and pharmaceutical compositions comprising them. The present invention further provides a novel amorphous Form of azilsartan medoxomil potassium, process for its preparation and pharmaceutical compositions comprising it. The present invention further provides a novel process for the preparation of azilsartan medoxomil potassium crystalline Form II.

摘要翻译： 本发明提供了一种新型的无定形形式的吖唑烷酸，其制备方法和包含它的药物组合物。 本发明还提供了叠氮基吗啉的新型结晶形式，其制备方法和包含它们的药物组合物。 本发明还提供了一种新型的无定形形式的吖唑烷酮莫昔米尔钾，其制备方法和包含它的药物组合物。 本发明还提供了制备吖唑烷酮咪唑啉钾晶型II的新方法。

公开(公告)号：EP3016935A2

公开(公告)日：2016-05-11

申请号：EP14819321.2

申请日：2014-07-03

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Narsingam, Mogili ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  MURALIDHARA REDDY, Dasari ,  NARSINGAM, Mogili ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D239/54

CPC分类号： C07D213/82 ,  C07C231/02 ,  C07D213/14 ,  C07D213/69 ,  C07D213/79 ,  C07D213/80 ,  C07D213/81 ,  C07D309/40 ,  C07D498/12

摘要： The present invention provides a novel processes for preparation of methyl 3-(benzyloxy)-5-(2,4-difluorobenzylcarbamoyl)-4-oxo-1-(2-oxoethyl)-1,4-dihydropyiridine-2-carboxylate using novel intermediates.

公开(公告)号：EP2872492A4

公开(公告)日：2016-01-13

申请号：EP13816744

申请日：2013-07-08

申请人： HETERO RESEARCH FOUNDATION ,  PARTHASARADHI REDDY BANDI ,  RATHNAKAR REDDY KURA ,  MURALIDHARA REDDY DASARI ,  VENKAT NARSIMHA REDDY ADULLA ,  VAMSI KRISHNA BANDI

发明人： PARTHASARADHI REDDY BANDI ,  RATHNAKAR REDDY KURA ,  MURALIDHARA REDDY DASARI ,  VENKAT NARSIMHA REDDY ADULLA ,  VAMSI KRISHNA BANDI

IPC分类号： C07D239/42 ,  C07D239/48

CPC分类号： C07D239/48 ,  C07D239/42

摘要： The present invention provides a commercially viable process for preparing rilpivirine and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate.

公开(公告)号：EP2872492A2

公开(公告)日：2015-05-20

申请号：EP13816744.0

申请日：2013-07-08

申请人： Hetero Research Foundation ,  Parthasaradhi, Reddy Bandi ,  Rathnakar Reddy, Kura ,  Muralidhara Reddy, Dasari ,  Venkat Narsimha Reddy, Adulla ,  Vamsi Krishna, Bandi

发明人： PARTHASARADHI REDDY, Bandi ,  RATHNAKAR REDDY, Kura ,  MURALIDHARA REDDY, Dasari ,  VENKAT NARSIMHA REDDY, Adulla ,  VAMSI KRISHNA, Bandi

IPC分类号： C07D239/48

CPC分类号： C07D239/48 ,  C07D239/42

摘要： The present invention provides a commercially viable process for preparing rilpivirine and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate.

摘要翻译： 本发明提供了使用新型中间体以高产率制备利比利林及其药学上可接受的酸加成盐的商业上可行的方法。