公开(公告)号：EP2167071A4

公开(公告)日：2013-01-02

申请号：EP08770940

申请日：2008-06-13

申请人： WAYNE STATE UNIVERSITY BOARD OF GOVERNORS ,  PHASE V PHARMACEUTICALS INC

发明人： MEYTHALER JAY M ,  TUEL STEPHEN M

IPC分类号： A61K31/195 ,  A61K9/00 ,  A61K47/00 ,  A61K47/02 ,  A61L9/04

CPC分类号： A61K45/06 ,  A61K9/0019 ,  A61K31/192 ,  A61K31/195 ,  A61K47/02

摘要： A high concentration baclofen solution is provided suitable for therapeutic use in a medical setting. A high concentration solution of baclofen in multivalent physiological ion solution such as artificial cerebrospinal fluid is provided with concentrations of baclofen of 10 mg/ml. Artificial cerebrospinal fluid is particularly advantageous as a baclofen solvent. A medical package is also provided for baclofen delivery to patients suffering from spasticity.

公开(公告)号：EP2167071B1

公开(公告)日：2020-03-18

申请号：EP08770940.8

申请日：2008-06-13

申请人： Wayne State University Board Of Governors ,  Phase V. Pharmaceuticals, Inc.

发明人： MEYTHALER, Jay, M. ,  TUEL, Stephen, M.

IPC分类号： A61K31/195 ,  A61K47/00 ,  A61L9/04 ,  A61K47/02 ,  A61K9/00 ,  A61K31/197 ,  A61K31/192

公开(公告)号：EP2167071A2

公开(公告)日：2010-03-31

申请号：EP08770940.8

申请日：2008-06-13

申请人： Wayne State University Board Of Governors ,  Phase V. Pharmaceuticals, Inc.

发明人： MEYTHALER, Jay, M. ,  TUEL, Stephen, M.

IPC分类号： A61K31/195 ,  A61K47/00 ,  A61L9/04

CPC分类号： A61K45/06 ,  A61K9/0019 ,  A61K31/192 ,  A61K31/195 ,  A61K47/02

摘要： A high concentration baclofen solution is provided suitable for therapeutic use in a medical setting. A high concentration solution of baclofen in multivalent physiological ion solution such as artificial cerebrospinal fluid is provided with concentrations of baclofen of 10 mg/ml. Artificial cerebrospinal fluid is particularly advantageous as a baclofen solvent. A medical package is also provided for baclofen delivery to patients suffering from spasticity.

摘要翻译： 提供适用于医疗环境中治疗用途的高浓度巴氯芬溶液。 提供高浓度的巴氯芬溶液，如人造脑脊液中的多价生理离子溶液，其浓度为10mg / ml的巴氯芬。 人造脑脊液作为巴氯芬溶剂是特别有利的。 还提供了药物包装，用于将巴氯芬递送给患有痉挛症的患者。