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公开(公告)号：EP2501281B1
公开(公告)日：2019-10-30
申请号：EP10832292.6
申请日：2010-11-19
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2.发明公开
公开(公告)号：EP3359208A1
公开(公告)日：2018-08-15
申请号：EP16784677.3
申请日：2016-10-07
发明人： ANGLE, Siddhesh , STRUNK, Michael , CHANG, Tak Lung , COALE, Bradford J. , STEBBINS, Greg , LIEPINS, Imants
CPC分类号： A61L27/20 , A61L27/12 , A61L27/306 , A61L27/3608 , A61L27/3616 , A61L27/365 , A61L27/422 , A61L27/427 , A61L27/46 , A61L27/56 , A61L2400/06 , A61L2400/08 , A61L2430/02 , A61L2430/24 , C08L5/04 , C08L1/28
摘要： Various embodiments disclosed relate to curable calcium phosphate compositions for use with porous structures and methods of using the same. In various embodiments, the present invention provides a curable calcium phosphate composition or a cured product thereof, with the curable calcium phosphate composition including calcium phosphate and a perfusion modifier. In various embodiments, the present invention provides an apparatus comprising a porous structure at least partially in contact with the curable calcium phosphate composition or a cured product thereof. The porous structure can include a porous substrate including a plurality of ligaments that define pores of the porous substrate, and a biocompatible metal coating on the plurality of ligaments of the porous substrate.
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公开(公告)号：EP3223722A1
公开(公告)日：2017-10-04
申请号：EP15805373.6
申请日：2015-11-24
摘要： An instrument for navigating to a target area near a subchondral defect of a bone and associated methods are disclosed. The instrument can include a body portion having a patient specific surface defining a negative impression of a portion of a skin surface of a patient, and a targeting device coupled to the body portion, the targeting device including a rail and at least one device portal configured to guide a device into a subchondral region of the bone for treatment at the target area.
摘要翻译： 公开了一种用于导航到骨软骨下缺陷附近的目标区域的仪器和相关方法。 该器械可以包括具有限定患者皮肤表面的一部分的负面印象的患者特异性表面的主体部分以及与主体部分连接的瞄准装置，瞄准装置包括轨道和配置的至少一个装置入口 引导装置进入骨的软骨下区域以在目标区域进行治疗。
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4.发明公开COORDINATE MAPPING SYSTEM FOR JOINT TREATMENT 审中-公开KOORDINATENZUORDNUNGSSYSTEM ZUR GELENKBEHANDLUNG
公开(公告)号：EP2501281A4
公开(公告)日：2017-05-31
申请号：EP10832292
申请日：2010-11-19
CPC分类号： A61B17/1764 , A61B90/11 , A61B2017/3411 , A61B2090/3937 , A61B2090/3966
摘要： A coordinate mapping system is provided for locating a defect in a bone. The system comprises a positioning instrument for controlled delivery of a device to a target site, the instrument comprising a main body and a rail extending from the main body, the rail including a series of indicia corresponding to predefined grid lines, and a template configured to overlay an image of a bone having a defect at the target site, the template including a predefined grid for determining a set of coordinates to locate the target site using the positioning instrument. A method of accessing a target site near a defect in a bone using the radial coordinate mapping system is also provided.
摘要翻译： 提供了坐标绘图系统来定位骨骼中的缺陷。 该系统包括用于将装置控制输送到目标部位的定位仪器，该仪器包括主体和从主体延伸的轨道，该轨道包括对应于预定义的网格线的一系列标记以及被配置成用于 将具有缺陷的骨骼的图像叠加在目标部位处，所述模板包括用于使用定位仪器来确定一组坐标以定位目标部位的预定义网格。 还提供了使用径向坐标映射系统访问骨骼中的缺陷附近的目标部位的方法。
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5.发明公开
公开(公告)号：EP2501314A4
公开(公告)日：2017-05-03
申请号：EP10832277
申请日：2010-11-19
CPC分类号： A61B17/8872 , A61B17/1635 , A61B17/17 , A61B17/1714 , A61B17/1742 , A61B17/1764 , A61B17/1775 , A61B17/1778 , A61B17/68 , A61B17/8802 , A61B2090/0807
摘要： Instruments and associated methods are disclosed for treating joints, and particularly bone tissue. One of these instruments may be a positioning instrument for controlled delivery of a device to a target site of the bone tissue being treated. The positioning instrument may comprise an alignment guide having a device portal for insertion of a device therethrough. The positioning instrument may have an indicator probe having an extended arm, and a handle portion for maneuvering the positioning instrument. Another instrument may be a device for placement through the device portal of the alignment guide and to the target site. The device may comprise an implant insertion tool, an injection catheter, a cavity creation tool such as a bone drill, for example, or the device may be an implantable device.
摘要翻译： 公开了用于治疗关节，特别是骨组织的器械和相关方法。 这些器械中的一个可以是用于将装置控制输送至正在治疗的骨组织的目标部位的定位器械。 定位器械可以包括具有用于通过其中插入装置的装置入口的对齐引导件。 定位仪器可以具有具有延伸臂的指示器探针和用于操纵定位仪器的手柄部分。 另一种仪器可以是用于通过对准引导装置的入口和目标位置放置的装置。 例如，该装置可以包括植入物插入工具，注射导管，诸如骨钻之类的腔创建工具，或者该装置可以是可植入装置。
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公开(公告)号：EP2892458B1
公开(公告)日：2019-08-14
申请号：EP13830086.8
申请日：2013-09-09
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7.发明授权
公开(公告)号：EP2967595B1
公开(公告)日：2018-10-24
申请号：EP14716489.1
申请日：2014-03-13
CPC分类号： A61B17/17 , A61B17/162 , A61B17/1675 , A61B17/1764 , A61B17/3403 , A61B17/3472 , A61B17/848 , A61B2017/3409
摘要： One embodiment disclosed provides a guide instrument for controlling the depth and trajectory of a surgical access device into a bone.
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公开(公告)号：EP2501342A4
公开(公告)日：2017-11-22
申请号：EP10832259
申请日：2010-11-19
CPC分类号： A61B17/1764 , A61B17/1742 , A61B17/1775 , A61B17/1778 , A61B17/8805 , A61B2017/564 , A61F2/28 , A61F2/4601 , A61F2002/2817 , A61F2002/2892 , A61F2002/4687
摘要： The embodiments provide devices and methods that both strengthen the bone and stimulate the bone. Bone fractures or non-unions are stabilized, integrated or healed, which results in reduction of a bone defect, such as a bone marrow lesion or edema. In addition, the distribution of forces in a joint are restored or altered to relieve pain. In general, a joint is evaluated by taking an image of the joint and one or more subchondral defects are detected. At least one of the subchondral defects may be diagnosed as the source of pain and an extent of treatment for the subchondral defect is determined. The disclosed devices and techniques are particularly suited for treating chronic defects or injuries, where the patient's natural healing response has not resolved the defect. The present disclosure also provides several exemplary treatment modalities for the different extents of treatment needed.
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公开(公告)号：EP2677946B1
公开(公告)日：2016-08-17
申请号：EP12714099.4
申请日：2012-02-22
CPC分类号： A61B17/3403 , A61B6/12 , A61B6/485 , A61B17/1703 , A61B17/1764 , A61B17/8805 , A61B17/8872 , A61B17/8897 , A61B90/39 , A61B2017/3411 , A61B2090/376 , A61B2090/3904 , A61B2090/3966 , A61B2090/3995 , A61M25/01
摘要： A system and associated instruments for locating, and accurately and controllably delivering, a device to an area sufficiently near a bone defect using anatomical landmarks is provided. The instruments allow the surgeon to navigate to the area around the bone defect quickly and easily, while also facilitating proper insertion of the device. In some embodiments, the defect is located on a femur. Guide instruments having a plurality of device portals are also provided for use as standalone instruments or as accessories to the system. In addition, a protective guide sleeve is provided for the insertion of small diameter devices.
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公开(公告)号：EP2501306B1
公开(公告)日：2020-02-12
申请号：EP10832285.0
申请日：2010-11-19
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