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    DEVICE FOR ENHANCED REMOVAL OF HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS HAVING AN ACTUATOR
    6.
    发明公开
    DEVICE FOR ENHANCED REMOVAL OF HEAT FROM SUBCUTANEOUS LIPID-RICH CELLS HAVING AN ACTUATOR 审中-公开
    DEVICE FOR热量从皮下脂RICH细胞与控制元件更好地去除

    公开(公告)号：EP3075336A2

    公开(公告)日：2016-10-05

    申请号：EP15201268.8

    申请日：2007-05-24

    申请人： Zeltiq Aesthetics, Inc.

    发明人： LEVINSON, Mitchell ,  ROSEN, Jesse, Nicasio

    IPC分类号： A61B18/02

    CPC分类号： A61H7/001 ,  A61F7/10 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/0228 ,  A61F2007/029 ,  A61H7/00 ,  A61H7/003 ,  A61H9/0057 ,  A61H9/0071 ,  A61H23/0254 ,  A61H23/0263 ,  A61H2201/165 ,  A61H2201/5082 ,  A61H2230/50

    摘要： A treatment device for removing heat from subcutaneous lipid-rich cells of a subject having an actuator that provides mechanical energy to the tissue. The mechanical energy provided may include a vibratory component that can range between low and ultra-high frequencies, and such energy may include various combinations of two or more frequencies tailored to produce the desired effect on the subcutaneous tissue. Disruption of adipose tissue cooled by an external treatment device may be enhanced by applying mechanical energy to cooled tissue. Furthermore, such mechanical energy may impart a vibratory effect, a massage effect, a pulsatile effect, or combinations thereof on the tissue.

    摘要翻译： 用于从具有在致动器的主体的皮下富脂细胞去除热量的处理装置没有提供机械能到组织。 提供可以包括一个振动部件的机械能并可以低和超高频之间的范围内，并且这样的能量可以包括适合于产生对皮下组织所期望的效果的两个或更多个频率的各种组合。 通过在外部处理装置冷却脂肪组织的破坏可通过施加机械能来冷却组织被增强。 进一步，谋求机械能可赋予振动效果，按摩效果，脉动效果，或在组织上或其组合。

    TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME
    7.
    发明公开
    TREATMENT SYSTEMS WITH FLUID MIXING SYSTEMS AND FLUID-COOLED APPLICATORS AND METHODS OF USING THE SAME 审中-公开
    与液体混合系统和液体处理系统风冷涂药器和方法及其使用

    公开(公告)号：EP2967977A2

    公开(公告)日：2016-01-20

    申请号：EP14720809.4

    申请日：2014-03-13

    申请人： Zeltiq Aesthetics, Inc.

    发明人： WEBER, Bryan, J. ,  COAKLEY, Joseph ,  BAKER, Mark, William ,  REEVE, Thomas, Burnell

    IPC分类号： A61F7/00 ,  A61F7/02

    摘要： A treatment system for cooling subcutaneous lipid-rich cells in a human subject includes an applicator and a control unit. The treatment system has a cooling mode for cooling tissue and a heating mode for warming tissue. The control unit includes a circulation circuit in fluid communication with the applicator, a chiller apparatus configured to chill fluid from the applicator circulation circuit, and a heater apparatus to warmed fluid from the applicator circulation circuit. The control unit mixes the chilled fluid and/or the warmed with fluid in the applicator circulation circuit control the temperature of the fluid circulated in the applicator.

    COMPOSITIONS AND TREATMENT SYSTEMS FOR IMPROVED COOLING OF LIPID-RICH TISSUE
    10.
    发明公开
    COMPOSITIONS AND TREATMENT SYSTEMS FOR IMPROVED COOLING OF LIPID-RICH TISSUE 审中-公开

    公开(公告)号：EP4279041A2

    公开(公告)日：2023-11-22

    申请号：EP23186988.4

    申请日：2015-01-30

    申请人： Zeltiq Aesthetics, Inc.

    发明人： O'NEIL, Michael P. ,  DEBENEDICTIS, Leonard C. ,  FRANGINEAS, George, Jr.

    IPC分类号： A61F7/00

    摘要： Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.