公开(公告)号：EP4279041A3

公开(公告)日：2024-01-24

申请号：EP23186988.4

申请日：2015-01-30

申请人： Zeltiq Aesthetics, Inc.

发明人： O'NEIL, Michael P. ,  DEBENEDICTIS, Leonard C. ,  FRANGINEAS, George, Jr.

IPC分类号： A61B18/02 ,  A61B18/00 ,  A61F7/00 ,  A61K31/047

摘要： Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

公开(公告)号：EP4279041A2

公开(公告)日：2023-11-22

申请号：EP23186988.4

申请日：2015-01-30

申请人： Zeltiq Aesthetics, Inc.

发明人： O'NEIL, Michael P. ,  DEBENEDICTIS, Leonard C. ,  FRANGINEAS, George, Jr.

IPC分类号： A61F7/00

摘要： Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

公开(公告)号：EP3099258A1

公开(公告)日：2016-12-07

申请号：EP15704186.4

申请日：2015-01-30

申请人： Zeltiq Aesthetics, Inc.

发明人： O'NEIL, Michael P. ,  DEBENEDICTIS, Leonard C. ,  FRANGINEAS, George, Jr.

IPC分类号： A61B18/02 ,  A61B18/00 ,  A61F7/00 ,  A61B90/00

CPC分类号： A61B18/02 ,  A61B18/0206 ,  A61B90/04 ,  A61B2018/00291 ,  A61B2018/00464 ,  A61B2018/00714 ,  A61B2018/00791 ,  A61B2018/00875 ,  A61B2018/00994 ,  A61B2018/0237 ,  A61B2018/0262 ,  A61B2090/0463 ,  A61B2090/065 ,  A61F7/00 ,  A61F7/007 ,  A61F2007/0003 ,  A61F2007/0004 ,  A61F2007/0019 ,  A61F2007/0036 ,  A61F2007/0045 ,  A61F2007/0047 ,  A61F2007/0052 ,  A61F2007/0056 ,  A61F2007/0075 ,  A61F2007/0087 ,  A61F2007/0093 ,  A61F2007/0096 ,  A61H1/006 ,  A61H1/008 ,  A61K31/045 ,  A61K31/047 ,  A61N7/00

摘要： Compositions and formulations for use with devices and systems that enable tissue cooling, such as cryotherapy applications, for alteration and reduction of adipose tissue are described. Aspects of the technology are further directed to methods, compositions and devices that provide protection of non-targeted cells (e.g., non-lipid-rich cells) from freeze damage during dermatological and related aesthetic procedures that require sustained exposure to cold temperatures. Further aspects of the technology include systems for enhancing sustained and/or replenishing release of cryoprotectant to a treatment site prior to and during cooling applications.

摘要翻译： 组合物和制剂用于与装置和系统使用确实使组织冷却,:如冷冻疗法应用，改变和减少脂肪组织的说明。 该技术的各方面涉及方法，此外，组合物和装置没有在皮肤病和相关的美容手术提供了从冻害非靶细胞（E. G.，非富脂细胞）保护也需要持续暴露在寒冷的气温。 该技术的其它方面包括用于之前和期间冷却应用增强持续和/或冷冻保护剂补益释放到治疗部位的系统。