公开(公告)号：EP3161161A4

公开(公告)日：2018-02-28

申请号：EP15812045

申请日：2015-06-26

申请人： 10X GENOMICS INC

发明人： JAROSZ MIRNA ,  HINDSON CHRISTOPHER ,  SCHNALL-LEVIN MICHAEL ,  NESS KEVIN DEAN ,  SAXONOV SERGE ,  HINDSON BENJAMIN J ,  STUELPNAGEL JOHN

IPC分类号： C12Q1/68

CPC分类号： C12N15/1058 ,  C12Q1/6806 ,  C12Q1/686 ,  C12Q2535/122 ,  C12Q2563/159 ,  C12Q2563/179

摘要： The present disclosure relates to methods and systems for sample processing and analyzing when the total quantity of input sample is low or when a target of interest is present as a relatively minor or rare population within the overall sample. The disclosure particularly relates to analyzing nucleic acid samples, including samples where a target nucleic acid of interest is present as a relatively low proportion of the overall nucleic acids.

公开(公告)号：EP3161160A4

公开(公告)日：2018-01-10

申请号：EP15811911

申请日：2015-06-26

申请人： 10X GENOMICS INC

发明人： HINDSON BENJAMIN J ,  HINDSON CHRISTOPHER MARTIN ,  SCHNALL-LEVIN MICHAEL ,  NESS KEVIN DEAN ,  JAROSZ MIRNA ,  SAXONOV SERGE ,  HARDENBOL PAUL ,  BHARADWAJ RAJIV ,  ZHENG GRACE X Y ,  BELGRADER PHILIP

IPC分类号： C12Q1/68 ,  C12N15/10 ,  C12P19/34

CPC分类号： C12N15/1065

摘要： Methods, compositions and systems for analyzing individual cells or cell populations through the partitioned analysis of contents of individual cells or cell populations. Individual cells or cell populations are co-partitioned with processing reagents for accessing cellular contents, and for uniquely identifying the contents of a given cell or cell population, and subsequently analyzing the cell's contents and characterizing it as having derived from an individual cell or cell population, including analysis and characterization of the cell's nucleic acids through sequencing.