公开(公告)号：EP4194855A1

公开(公告)日：2023-06-14

申请号：EP22209155.5

申请日：2020-10-09

申请人： 10X Genomics, Inc.

发明人： MCDERMOTT, Geoffrey ,  TAYLOR, Sarah ,  BOUTET, Stephane Claude ,  MCDONNELL, Wyatt James ,  STUBBINGTON, Michael John Terry

IPC分类号： G01N33/543 ,  C12Q1/6806

摘要： Provided herein are methods and systems for measuring secreted cytokines or other analytes from single cells. The methods disclosed herein include the use of analyte-specific and/or barcoded binding agents (e.g., antibodies) and beads in partitions (e.g., droplets or wells) to measure such analytes on a single cell basis. Further described herein are methods comprising the use of hydrogel-encapsulated cells (e.g., cell beads) to measure secreted and/or cellular analytes from single cells.

公开(公告)号：EP4022309A1

公开(公告)日：2022-07-06

申请号：EP20800449.9

申请日：2020-10-09

申请人： 10X Genomics, Inc.

发明人： MCDERMOTT, Geoffrey ,  TAYLOR, Sarah ,  BOUTET, Stephane Claude ,  MCDONNELL, Wyatt James ,  STUBBINGTON, Michael John Terry

IPC分类号： G01N33/543 ,  C12Q1/6806

公开(公告)号：EP3919626A1

公开(公告)日：2021-12-08

申请号：EP21166292.9

申请日：2018-12-07

申请人： 10X Genomics, Inc.

发明人： BOUTET, Stephane Claude ,  LUCERO, Michael Ybarra ,  MIKKELSEN, Tarjei Sigurd ,  PFEIFFER, Katherine

IPC分类号： C12Q1/6816 ,  C12Q1/6806

摘要： The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.

公开(公告)号：EP4403644A3

公开(公告)日：2024-10-16

申请号：EP24179541.8

申请日：2018-12-07

申请人： 10X Genomics, Inc.

发明人： BOUTET, Stephane Claude ,  LUCERO, Michael Ybarra ,  MIKKELSEN, Tarjei Sigurd ,  PFEIFFER, Katherine

IPC分类号： C12Q1/6816 ,  C12Q1/6806

摘要： The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.

公开(公告)号：EP4403644A2

公开(公告)日：2024-07-24

申请号：EP24179541.8

申请日：2018-12-07

申请人： 10X Genomics, Inc.

发明人： BOUTET, Stephane Claude ,  LUCERO, Michael Ybarra ,  MIKKELSEN, Tarjei Sigurd ,  PFEIFFER, Katherine

IPC分类号： C12Q1/6806

CPC分类号： C12Q1/6816 ,  C12Q1/6806

摘要： The present disclosure provides methods, systems, and compositions for parallel processing of nucleic acid samples. Methods and systems of the present disclosure comprise the use of sample-specific barcode sequences, which facilitate the multiplexing of samples, detection of discrete cell populations within a pooled population, and detection of partitions comprising more than one cell.

公开(公告)号：EP3568494A1

公开(公告)日：2019-11-20

申请号：EP18829641.2

申请日：2018-12-07

申请人： 10X Genomics, Inc.

发明人： BOUTET, Stephane Claude ,  LUCERO, Michael Ybarra ,  MIKKELSEN, Tarjei Sigurd ,  PFEIFFER, Katherine

IPC分类号： C12Q1/6816