公开(公告)号：EP4357493A3

公开(公告)日：2024-07-24

申请号：EP24158974.6

申请日：2014-06-26

申请人： 10X Genomics, Inc.

发明人： HINDSON, Benjamin ,  HINDSON, Christopher ,  SCHNALL-LEVIN, Michael ,  NESS, Kevin ,  JAROSZ, Mirna ,  MASQUELIER, Donald ,  SAXONOV, Serge ,  MERRILL, Landon ,  PRICE, Andrew ,  HARDENBOL, Paul ,  LI, Yuan

IPC分类号： C40B20/00 ,  C12Q1/6813 ,  C12Q1/6869 ,  C12Q1/6876

CPC分类号： C12Q1/6813 ,  C12Q1/6869 ,  C12Q1/6876

摘要： This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provided herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.

公开(公告)号：EP3013957B1

公开(公告)日：2018-09-26

申请号：EP14817610.0

申请日：2014-06-26

申请人： 10X Genomics, Inc.

发明人： HINDSON, Benjamin ,  HINDSON, Christopher ,  SCHNALL-LEVIN, Michael ,  NESS, Kevin ,  JAROSZ, Mirna ,  MASQUELIER, Donald ,  SAXONOV, Serge ,  MERRILL, Landon ,  PRICE, Andrew ,  HARDENBOL, Paul ,  LI, Yuan

IPC分类号： C12N15/10 ,  C12Q1/68 ,  G01N33/566 ,  G06F19/20

CPC分类号： C12Q1/6869 ,  C12Q1/6813 ,  C12Q1/6876 ,  C12Q2525/161 ,  C12Q2565/514

摘要： This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.

公开(公告)号：EP3013957A2

公开(公告)日：2016-05-04

申请号：EP14817610.0

申请日：2014-06-26

申请人： 10X Genomics, Inc.

发明人： HINDSON, Benjamin ,  HINDSON, Christopher ,  SCHNALL-LEVIN, Michael ,  NESS, Kevin ,  JAROSZ, Mirna ,  MASQUELIER, Donald ,  SAXONOV, Serge ,  MERRILL, Landon ,  PRICE, Andrew ,  HARDENBOL, Paul ,  LI, Yuan

IPC分类号： C12N15/10 ,  C12Q1/68 ,  G01N33/566 ,  G06F19/20

CPC分类号： C12Q1/6869 ,  C12Q1/6813 ,  C12Q1/6876 ,  C12Q2525/161 ,  C12Q2565/514

摘要： This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provides herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.

公开(公告)号：EP4357493A2

公开(公告)日：2024-04-24

申请号：EP24158974.6

申请日：2014-06-26

申请人： 10X Genomics, Inc.

发明人： HINDSON, Benjamin ,  HINDSON, Christopher ,  SCHNALL-LEVIN, Michael ,  NESS, Kevin ,  JAROSZ, Mirna ,  MASQUELIER, Donald ,  SAXONOV, Serge ,  MERRILL, Landon ,  PRICE, Andrew ,  HARDENBOL, Paul ,  LI, Yuan

IPC分类号： C40B20/00

CPC分类号： C12Q1/6813 ,  C12Q1/6869 ,  C12Q1/6876

摘要： This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provided herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.

公开(公告)号：EP3467160A1

公开(公告)日：2019-04-10

申请号：EP18189200.1

申请日：2014-06-26

申请人： 10X Genomics, Inc.

发明人： HINDSON, Benjamin ,  HINDSON, Christopher ,  SCHNALL-LEVIN, Michael ,  NESS, Kevin ,  JAROSZ, Mirna ,  MASQUELIER, Donald ,  SAXONOV, Serge ,  MERRILL, Landon ,  PRICE, Andrew ,  HARDENBOL, Paul ,  LI, Yuan

IPC分类号： C40B50/06 ,  C40B20/00

摘要： This disclosure provides methods and compositions for sample processing, particularly for sequencing applications. Included within this disclosure are bead compositions, such as diverse libraries of beads attached to large numbers of oligonucleotides containing barcodes. Often, the beads provided herein are degradable. For example, they may contain disulfide bonds that are susceptible to reducing agents. The methods provided herein include methods of making libraries of barcoded beads as well as methods of combining the beads with a sample, such as by using a microfluidic device.