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7 条记录 (耗时 0.012 秒)

    Method for storage of labile protein materials
    1.
    发明公开
    Method for storage of labile protein materials 失效
    Verfahren zur Lagerung labiler蛋白质。

    公开(公告)号：EP0675361A2

    公开(公告)日：1995-10-04

    申请号：EP95110925.5

    申请日：1988-07-12

    申请人： Abbott Laboratories

    发明人： Ching, Shanfun ,  Billing, Patricia A. ,  Gordon, Julian

    IPC分类号： G01N33/543 ,  G01N33/558 ,  G01N33/531 ,  G01N33/58

    CPC分类号： G01N33/587 ,  G01N30/90 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/54393 ,  G01N33/558 ,  G01N33/585 ,  G01N33/76 ,  Y10S435/967 ,  Y10S435/97 ,  Y10S435/975 ,  Y10S436/801 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/826 ,  Y10S514/97

    摘要： The present invention relates to (1) a method for storing labile proteins which prevents aggregation and inactivation of the proteins when maintained in the dry state wherein said proteins may be rapidly solubilized, which method comprises drying the protein on a substrate in the presence of an aqueous medium containing a meta-soluble protein, (2) a product produced therefrom comprising a solid substrate upon which is impregnated and dried a labelled protein in the presence of an aqueous medium containing a meta-soluble protein and (3) a composition of matter comprising a colloidal particle labelled reagent and a sufficient amount of a meta-soluble protein to allow resolubilization from a dried state and chromatographic solvent transport of said colloidal particle labelled reagent.

    摘要翻译： 本发明涉及（1）一种储存不稳定蛋白质的方法，其在保持干燥状态时可防止蛋白质的聚集和失活，其中所述蛋白质可被快速溶解，该方法包括在存在下干燥基质上的蛋白质 含有可溶性蛋白质的水性介质，（2）由其制备的产品，其中含有固体底物，在含有可溶性蛋白质的水性介质的存在下，浸渍并干燥标记的蛋白质，（3）物质组成 包括胶体颗粒标记的试剂和足够量的可溶性蛋白质，以允许从干燥状态重新溶解和所述胶体颗粒标记的试剂的色谱溶剂输送。

    Method for storage of labile protein materials
    6.
    发明公开
    Method for storage of labile protein materials 失效
    贮存不稳定蛋白质材料的方法

    公开(公告)号：EP0675361A3

    公开(公告)日：1995-10-25

    申请号：EP95110925.5

    申请日：1988-07-12

    申请人： Abbott Laboratories

    发明人： Ching, Shanfun ,  Billing, Patricia A. ,  Gordon, Julian

    IPC分类号： G01N33/543 ,  G01N33/558 ,  G01N33/531 ,  G01N33/58

    CPC分类号： G01N33/587 ,  G01N30/90 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/54393 ,  G01N33/558 ,  G01N33/585 ,  G01N33/76 ,  Y10S435/967 ,  Y10S435/97 ,  Y10S435/975 ,  Y10S436/801 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/826 ,  Y10S514/97

    摘要： The present invention relates to (1) a method for storing labile proteins which prevents aggregation and inactivation of the proteins when maintained in the dry state wherein said proteins may be rapidly solubilized, which method comprises drying the protein on a substrate in the presence of an aqueous medium containing a meta-soluble protein, (2) a product produced therefrom comprising a solid substrate upon which is impregnated and dried a labelled protein in the presence of an aqueous medium containing a meta-soluble protein and (3) a composition of matter comprising a colloidal particle labelled reagent and a sufficient amount of a meta-soluble protein to allow resolubilization from a dried state and chromatographic solvent transport of said colloidal particle labelled reagent.

    摘要翻译： 本发明涉及（1）用于储存不稳定蛋白质的方法，所述不稳定蛋白质当保持干燥状态时能够使蛋白质聚集和失活，其中所述蛋白质可以被快速溶解，该方法包括在存在 （2）由其制备的产品，其包含固体基质，在含有可溶性蛋白质的水性介质存在下，将标记的蛋白质浸渍并干燥，并且（3）物质组合物 其包含胶体颗粒标记的试剂和足够量的可溶性蛋白质以允许所述胶体颗粒标记的试剂从干燥状态重新溶解和色谱溶剂转移。

    Process for immunochromatography with colloidal particles
    7.
    发明公开
    Process for immunochromatography with colloidal particles 失效
    VerfahrenfürImmunochromatographie mit Kolloidteilchen。

    公开(公告)号：EP0299428A2

    公开(公告)日：1989-01-18

    申请号：EP88111134.8

    申请日：1988-07-12

    申请人： ABBOTT LABORATORIES

    发明人： Ching, Shanfun ,  Gordon, Julian ,  Billing, Patricia A.

    IPC分类号： G01N33/543 ,  G01N33/558

    CPC分类号： G01N33/587 ,  G01N30/90 ,  G01N33/54366 ,  G01N33/54386 ,  G01N33/54393 ,  G01N33/558 ,  G01N33/585 ,  G01N33/76 ,  Y10S435/967 ,  Y10S435/97 ,  Y10S435/975 ,  Y10S436/801 ,  Y10S436/807 ,  Y10S436/808 ,  Y10S436/826 ,  Y10S514/97

    摘要： The present invention relates to improved specific binding assay methods, kits and devices utilizing chromatographically mobile specific binding reagents labelled with colloidal particles. Specific binding reagents labelled with colloidal particles such as gold and selenium may be subjected to rapid chromatographic solvent transport on chromatographic media by means of selected solvents and chromatographic transport facilitating agents. Further, impregnation of solid substrate materials with labile protein materials including colloidal particle and enzyme labelled reagents in the presence of meta-soluble proteins provides for the rapid resolubilization of such materials which have been dried onto such substrate materials.

    摘要翻译： 本发明涉及改进的特异性结合测定方法，使用用胶体颗粒标记的色谱移动特异性结合试剂的试剂盒和装置。 用胶体颗粒如金和硒标记的特异性结合剂可以通过选择的溶剂和色谱传输促进剂在色谱介质上进行快速色谱溶剂转移。 此外，在存在可溶性蛋白质的情况下，用包括胶体颗粒和酶标记的试剂在内的不稳定蛋白质材料浸渍固体底物材料提供了已经干燥到这种基底材料上的这种材料的快速再溶解。