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公开(公告)号：EP4340881A1
公开(公告)日：2024-03-27
申请号：EP22806958.9
申请日：2022-05-12
申请人： ABL Bio Inc.
发明人： PARK, Kyungjin , SONG, Daehae , JUNG, Jinwon , SUNG, Byungje , YUN, Hyesu , SHIN, Jung-Won , AN, Sungwon , KIM, Juhee , LEE, Bora , AHN, Jinhyung , KIM, Dongin , KIM, Donghwan , SON, Yong-Gyu , PAK, Youngdon
IPC分类号： A61K39/395 , A61P25/28 , C07K16/18
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公开(公告)号：EP3985022A1
公开(公告)日：2022-04-20
申请号：EP20822425.3
申请日：2020-06-15
申请人： ABL Bio, Inc.
发明人： AN, Sungwon , AHN, Jinhyung , SUNG, Byungje , KIM, Dongin , SONG, Daehae , EOM, Jaehyun , SON, Yong-Gyu , PARK, Kyungjin , KIM, Juhee , JUNG, Jinwon , LEE, Bora , YUN, Hyesu
摘要： The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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公开(公告)号：EP4268842A3
公开(公告)日：2024-05-22
申请号：EP23178097.4
申请日：2020-06-15
申请人： ABL Bio, Inc.
发明人： AN, Sungwon , AHN, Jinhyung , SUNG, Byungje , KIM, Dongin , SONG, Daehae , EOM, Jaehyun , SON, Yong-Gyu , PARK, Kyungjin , KIM, Juhee , JUNG, Jinwon , LEE, Bora , YUN, Hyesu
CPC分类号： A61P25/28 , C07K16/2863 , A61K2039/50520130101 , C07K2317/3120130101 , C07K2317/56520130101 , C07K2317/3320130101 , C07K2317/3420130101 , C07K2317/7720130101 , C07K2317/9220130101 , C07K2317/62220130101 , C07K16/2896 , C07K16/18
摘要： The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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公开(公告)号：EP4268842A2
公开(公告)日：2023-11-01
申请号：EP23178097.4
申请日：2020-06-15
申请人： ABL Bio, Inc.
发明人： AN, Sungwon , AHN, Jinhyung , SUNG, Byungje , KIM, Dongin , SONG, Daehae , EOM, Jaehyun , SON, Yong-Gyu , PARK, Kyungjin , KIM, Juhee , JUNG, Jinwon , LEE, Bora , YUN, Hyesu
IPC分类号： A61K39/00
摘要： The present disclosure relates to a bispecific antibody that specifically binds to alpha-synuclein and IGF1R, and an use of the bispecific antibody for the prevention, treatment and / or diagnosis of synucleinopatheis associated with alpha-synuclein or alpha-synuclein aggregates, and can allow the alpha-synuclein antibody or an antigen-binding fragment thereof to penetrate the blood brain barrier to exert its action in the brain, and extend the half-life to maintain the efficacy for a long time.
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