公开(公告)号：EP1624785A4

公开(公告)日：2007-10-17

申请号：EP04703672

申请日：2004-01-20

申请人： AETHLON MEDICAL INC

发明人： TULLIS RICHARD H

IPC分类号： A61L2/02 ,  A61B20060101 ,  A61B1/00 ,  A61M1/14 ,  A61M1/34 ,  A61M1/38 ,  A61M37/00

CPC分类号： A61M1/3486 ,  A61L2/02 ,  A61L2/022 ,  A61M1/3472

摘要： The present invention relates to a method for using lectins that bind to pathogens having high mannose surface glycoproteins or fragments thereof which contain high mannose glycoproteins, to remove them from infected blood or plasma in an extracorporeal setting. Accordingly, the present invention provides a method for reducing viral load in an individual comprising the steps of obtaining blood or plasma from the individual, passing the blood or plasma through a porous hollow fiber membrane wherein lectin molecules are immobilized within the porous exterior portion of the membrane, collecting pass-through blood or plasma and reinfusing the pass-through blood or plasma into the individual.

公开(公告)号：EP1993600A4

公开(公告)日：2014-02-19

申请号：EP07752778

申请日：2007-03-09

申请人： AETHLON MEDICAL INC

发明人： ICHIM THOMAS ,  TULLIS RICHARD H

IPC分类号： A61M1/36 ,  B01D15/00 ,  B01J20/28 ,  B01J20/32

CPC分类号： A61M1/362 ,  A61M1/16 ,  A61M1/3496 ,  A61M1/3679 ,  B01D15/00 ,  B01J20/28014 ,  B01J20/3242

摘要： The invention described herein teaches methods of removing microvesicular particles, which include but are not limited to exosomes, from the systemic circulation of a subject in need thereof with the goal of reversing antigen-specific and antigen-nonspecific immune suppression. Said microvesicular particles could be generated by host cells that have been reprogrammed by neoplastic tissue, or the neoplastic tissue itself. Compositions of matter, medical devices, and novel utilities of existing medical devices are disclosed.

公开(公告)号：EP2318031A4

公开(公告)日：2012-09-12

申请号：EP09759338

申请日：2009-06-03

申请人： AETHLON MEDICAL INC

发明人： TULLIS RICHARD H ,  HANDLEY HAROLD H JR ,  DUFFIN R PAUL ,  JOYCE JAMES A

IPC分类号： A61K38/16 ,  A61K38/13 ,  A61K38/21 ,  A61M1/34 ,  A61P31/12 ,  A61P31/18

CPC分类号： A61K38/21 ,  A61K38/13 ,  A61M1/3472 ,  A61M1/3479 ,  A61M2202/206

摘要： Embodiments of the present invention relate to enhanced antiviral therapy methods, devices, and kits for treating viral infections. The disclosed enhanced antiviral therapy methods, devices, and kits enhance the efficacy of an antiviral therapy by administering a lectin affinity hemodialysis treatment to an individual suffering from viral infection in combination with the antiviral therapy.

公开(公告)号：EP2591359A4

公开(公告)日：2014-01-22

申请号：EP11804372

申请日：2011-07-07

申请人： AETHLON MEDICAL INC

发明人： TULLIS RICHARD H ,  DUFFIN PAUL

IPC分类号： G01N33/53 ,  C12Q1/06 ,  G01N33/58

CPC分类号： G01N33/57492 ,  G01N33/5695 ,  G01N33/56966 ,  G01N33/5743 ,  G01N33/57446 ,  G01N33/57449 ,  G01N2333/4724

公开(公告)号：EP2344233A4

公开(公告)日：2012-03-21

申请号：EP09815068

申请日：2009-09-15

申请人： AETHLON MEDICAL INC

发明人： TULLIS RICHARD H ,  HANDLEY HAROLD H ,  JOYCE JAMES A ,  DUFFIN PAUL

IPC分类号： C12N7/02 ,  A61K39/29 ,  A61M1/34 ,  A61M37/00

CPC分类号： C12N7/00 ,  A61M1/3679 ,  A61M2202/206 ,  C12N2770/24251