专利检索 ap:("AICHI PREFECTURE" OR "OTSUKA PHARMA CO LTD") AND inv:"KUZUSHIMA KIYOTAKA" 第 1 页

1.

发明公开
EPITOPE/PEPTIDE RECOGNIZED BY HLA-A2402-RESTRICTED Ep-CAM-SPECIFIC CTL AND USE OF THE SAME 有权
标题翻译：由HLA-A2402-限制的Ep-CAM特异性CTL表位的认可/肽及其用途

公开(公告)号：EP1715042A4

公开(公告)日：2008-01-09

申请号：EP05703824

申请日：2005-01-19

申请人： AICHI PREFECTURE , OTSUKA PHARMA CO LTD

发明人： KUZUSHIMA KIYOTAKA

IPC分类号： C12N15/12 , A61K31/7088 , A61K38/00 , A61K39/00 , A61K48/00 , A61P35/00 , A61P43/00 , C07K7/06 , C07K14/47 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/06 , C12N5/10 , C12P21/02 , C12Q1/02

CPC分类号： A61K31/7088 , A61K38/00 , A61K39/00 , C07K14/4748

摘要： A peptide comprising the amino acid sequence represented by SEQ ID NO:1; a peptide comprising the amino acid sequence represented by SEQ ID NO:2; or a mutant peptide comprising an amino acid sequence derived from an amino acid sequence represented by SEQ ID NO:1 or 2 by addition, deletion or substitution of one or more amino acids and being capable of forming a complex with an HLA-A2402 molecule that can be recognized by HLA-A2402-restricted cytotoxic T lymphocytes or being capable of inducing the same. Such a peptide is useful as a cancer vaccine for epithelial cancer patients having HLA-A2402.