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公开(公告)号：EP0639070B1
公开(公告)日：2005-08-03
申请号：EP93911061.5
申请日：1993-05-04
IPC分类号： A61K9/00
CPC分类号： A61K9/0048 , Y02A50/473 , Y10S514/839 , Y10S514/84 , Y10S514/912 , Y10S514/915
摘要： Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.
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公开(公告)号：EP0639070B2
公开(公告)日：2010-09-08
申请号：EP93911061.5
申请日：1993-05-04
IPC分类号： A61K9/00
CPC分类号： A61K9/0048 , Y02A50/473 , Y10S514/839 , Y10S514/84 , Y10S514/912 , Y10S514/915
摘要： Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.
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公开(公告)号：EP0639070A1
公开(公告)日：1995-02-22
申请号：EP93911061.0
申请日：1993-05-04
IPC分类号： A61K9 , A61K33 , A61K47 , A61L2 , A61P27 , A61P37 , C08K3 , C08K5 , C08L29 , C08L79 , C08L101
CPC分类号： A61K9/0048 , Y02A50/473 , Y10S514/839 , Y10S514/84 , Y10S514/912 , Y10S514/915
摘要： Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.
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