公开(公告)号：EP1353709B2

公开(公告)日：2011-09-14

申请号：EP02710004.9

申请日：2002-01-11

Applicant: Novartis AG ,  Novartis Pharma GmbH

Inventor： SCHWIND, Peter ,  SCHERER, Anton

IPC: A61L12/14

CPC classification number: C11D3/32 ,  A61L12/147 ,  C11D3/0078 ,  C11D3/221 ,  C11D3/48 ,  C11D7/268 ,  C11D7/3218 ,  C11D7/3245 ,  C11D7/3272 ,  Y10S514/84

Abstract: The present invention relates to contact lens care product comprising dexpanthenol. The invention similarly relates to the usage of a contact lens care compositions of this kind for cleaning and optionally disinfecting contact lenses.

公开(公告)号：EP2049163A1

公开(公告)日：2009-04-22

申请号：EP07796861.8

申请日：2007-07-13

Applicant: NOVARTIS AG

Inventor： LANE, Jennifer Dawn ,  PERREAULT, Stephen Raymond ,  BEAULLIEU, Elizabeth Hickson

IPC: A61L12/08 ,  A61L12/12 ,  A61L12/14 ,  C11D3/00 ,  C11D3/39 ,  C11D3/37 ,  C11D3/40 ,  C11D3/12 ,  C11D3/14

CPC classification number: C11D3/0078 ,  A61L12/086 ,  A61L12/124 ,  A61L12/142 ,  C11D1/345 ,  C11D3/1246 ,  C11D3/128 ,  C11D3/14 ,  C11D3/3726 ,  C11D3/3947 ,  C11D3/40 ,  C11D11/0058 ,  Y10S134/901 ,  Y10S514/839 ,  Y10S514/84

Abstract: The present invention provides a lens care kit for disinfecting and cleaning contact lenses. The lens care kit of the invention allows customers to visually identify when their lenses are disinfected, clean, and ready to wear. The invention is relied on color change to indicate the readiness of disinfection and cleaning of contact lenses.

公开(公告)号：EP1572253B1

公开(公告)日：2007-10-10

申请号：EP03795889.9

申请日：2003-12-12

Applicant: Novartis AG ,  Novartis Pharma GmbH

Inventor： TSAO, Fu-Pao ,  LINDLEY, Karen, Frances

IPC: A61L12/14 ,  C11D3/37

CPC classification number: C11D3/48 ,  A61L12/08 ,  A61L12/141 ,  A61L12/142 ,  C11D1/72 ,  C11D3/0078 ,  Y10S514/84

Abstract: An buffered aqueous contact lens disinfecting solution having much lower concentration of disinfecting agents, and less irritating to the eye. The solutions have a tonicity of 200 to 450 mOsm/kg, a pH of between 6 and 8, and a concentration of chloride ions below 1500 ppm. Despite having less than 1 ppm of antimicrobial, the solutions are effective against C. albicans within 15 minutes of contact.

公开(公告)号：EP1738778A1

公开(公告)日：2007-01-03

申请号：EP06020462.5

申请日：2002-01-11

Applicant: Novartis AG ,  Novartis Pharma GmbH

Inventor： Schwind, Peter ,  Scherer, Anton

IPC: A61L12/14

CPC classification number: C11D3/32 ,  A61L12/147 ,  C11D3/0078 ,  C11D3/221 ,  C11D3/48 ,  C11D7/268 ,  C11D7/3218 ,  C11D7/3245 ,  C11D7/3272 ,  Y10S514/84

Abstract: The present invention relates to contact lens care product comprising dexpanthenol and D-sorbit. The invention similarly relates to the usage of a contact lens care compositions of this kind for cleaning and optionally disinfecting contact lenses.

Abstract translation: 隐形眼镜护理产品技术领域本发明涉及隐形眼镜护理产品，其包含右美沙芬和D-山梨糖醇。 本发明类似地涉及这种用于清洁和任选地消毒隐形眼镜的隐形眼镜护理组合物的用途。

公开(公告)号：EP1732617A1

公开(公告)日：2006-12-20

申请号：EP05733007.8

申请日：2005-03-30

Applicant: Advanced Medical Optics, Inc.

Inventor： YU, Zhi-Jian

IPC: A61L12/14 ,  A01N33/04 ,  A01N59/00 ,  A01N47/44 ,  A01N41/08 ,  A01N33/12

CPC classification number: A01N33/04 ,  Y10S514/839 ,  Y10S514/84 ,  A01N2300/00

Abstract: A multi-purpose contact lens care solution having high activity against fungi and certain bacteria comprising, in liquid aqueous medium, an alkylamine having the following Formula (I) , R1 R2 I R3 where R1 is a C13-17 alkylamine, and R2 and R3 are each independently H or -CH3, and a non-ionic surfactant. The solution may optionally also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and/or a tonicity component. This solution additionally prevents losses in ocular tissue membrane integrity during contact lens wear.

公开(公告)号：EP0639070B1

公开(公告)日：2005-08-03

申请号：EP93911061.5

申请日：1993-05-04

Applicant: ALCON LABORATORIES, INC.

Inventor： CHOWHAN, Masood ,  Dassanayake, Nissanke, Lakshman

IPC: A61K9/00

CPC classification number: A61K9/0048 ,  Y02A50/473 ,  Y10S514/839 ,  Y10S514/84 ,  Y10S514/912 ,  Y10S514/915

Abstract: Aqueous ophthalmic compositions containing water-soluble borate-polyol complexes are useful in aqueous ophthalmic compositions containing polyvinyl alcohol. These compositions provide the benefits of a borate buffering system, such as enhanced antimicrobial activity, without the problems associated with the use of borate and pol, such as formation of borate-polyvinyl alcohol complexes which are water-insoluble.

公开(公告)号：EP1339278B1

公开(公告)日：2004-12-08

申请号：EP01984771.4

申请日：2001-11-27

Applicant: Novartis AG ,  Novartis-Erfindungen Verwaltungsgesellschaft m.b.H.

Inventor： MOWREY-MCKEE, Mary, Flowers ,  AJELLO, Marc, Lee

IPC: A01N1/00

CPC classification number: A01N33/08 ,  A01N47/44 ,  Y10S514/839 ,  Y10S514/84 ,  A01N61/00 ,  A01N59/00 ,  A01N43/36 ,  A01N33/12 ,  A01N2300/00

Abstract: Compositions effective as disinfecting solutions for ophthalmic devices such as contact lenses are provided. The compositions include a microbicide, preferably polyhexamethylene biguanide or alexidine, and a water soluble salt of a bis-aminopolyol, preferably 1,3-bis(tris[hydroxymethyl]methylamino)propane, as a buffering agent.

公开(公告)号：EP0731714B1

公开(公告)日：2003-07-16

申请号：EP95932460.9

申请日：1995-09-19

Applicant: ALCON LABORATORIES, INC.

Inventor： PARK, Joonsup

IPC: A61L2/00 ,  C08G65/32 ,  A01N33/12

CPC classification number: A01N33/12 ,  A61L12/145 ,  C08G65/33303 ,  Y10S514/839 ,  Y10S514/84

Abstract: PEO-containing quaternary ammonium compounds have good broad spectrum antimicrobial activity. These compounds are useful in pharmaceutical compositions as preservatives and in contact lens care compositions as preservatives and/or disinfectants.

公开(公告)号：EP1140224A1

公开(公告)日：2001-10-10

申请号：EP99962900.9

申请日：1999-11-29

Applicant: BAUSCH & LOMB INCORPORATED

Inventor： XIA, Earning

IPC: A61L12/14

CPC classification number: A61L12/142 ,  A61L12/141 ,  A61L12/145 ,  C11D3/0078 ,  C11D3/48 ,  Y10S134/901 ,  Y10S514/839 ,  Y10S514/84 ,  Y10S514/912 ,  Y10S514/915 ,  Y10S514/97 ,  Y10S514/975

Abstract: The present invention is directed to a biguanide-containing disinfecting solution containing tyloxapol in combination with a poloxamine for stabilizing the biguanide, which is especially useful for contact-lens solutions that provide enhanced disinfecting and enhanced cleaning efficacy. The method of the present invention comprises cleaning and disinfecting a contact lens with the above-described solution.

Abstract translation: 本发明涉及一种含有双酚A的消毒溶液，其含有与用于稳定双胍的泊洛沙胺组合的泰洛沙泊，其特别适用于提供增强的消毒和增强的清洁功效的隐形眼镜溶液。 本发明的方法包括用上述溶液清洁和消毒隐形眼镜。

公开(公告)号：EP0948357A1

公开(公告)日：1999-10-13

申请号：EP97947519.0

申请日：1997-11-17

Applicant: ALCON LABORATORIES, INC.

Inventor： ASGHARIAN, Bahram

IPC: A61K9 ,  A61K31 ,  A61K33 ,  A61K47 ,  A61L2 ,  A61L12 ,  A61P27 ,  G02C13

CPC classification number: A61K33/22 ,  A61K9/0048 ,  A61K31/13 ,  A61K31/138 ,  A61K47/18 ,  A61L12/147 ,  Y10S514/839 ,  Y10S514/84 ,  Y10S514/912 ,  A61K2300/00

Abstract: The use of low molecular weight amino alcohols in ophthalmic compositions is described. These compounds have been found to enhance the efficacy of anti-microbial preservatives. Particularly preferred amino alcohols are 2-amino-2-methyl-1-propanol (AMP), 2-dimethylamino-2-methyl-1-propanediol (DMAMP), 2-amino-2-ethyl-1,3-propanediol (AEPD), 2-amino-2-methyl-1,3-propanediol (AMPD), and 2-amino-1-butanol (AB). The ophthalmic compositions further optionally comprise a borate/polyol buffer system and an alkylamine.