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公开(公告)号：EP0669803A1
公开(公告)日：1995-09-06
申请号：EP94929286.0
申请日：1994-09-21
CPC分类号： A01N37/20 , A61L12/12 , Y10S514/84
摘要： The use of certain amidoamines to disinfect contact lenses and preserve ophthalmic compositions is described. Ophthalmic compositions containing these compounds as disinfecting agents or preservatives are also described. The amidoamines utilized in the present invention have potent antibacterial and antifungal activity, and are chemically compatible with inorganic ions and other materials utilized in ophthalmic compositions.
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2.发明公开POLYMERIC QUATERNARY AMMONIUM COMPOUNDS AND THEIR USE AS OPHTHALMIC ANTIMICROBIALS 失效聚合物型季铵化合物和它们作为眼科抗菌物质使用
公开(公告)号：EP0880351A1
公开(公告)日：1998-12-02
申请号：EP96906426.0
申请日：1996-02-14
发明人： KYBA, Evan, P. , PARK, Joonsup
CPC分类号： C07C215/90 , C07C211/63
摘要： The invention relates to polymeric quaternary ammonium compounds which are useful as disinfectants and/or preservatives in ophthalmic compositions.
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3.发明授权AMINOBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS 有权AMINOBIGUANIDE及其用途隐形眼镜消毒保鲜药物制剂
公开(公告)号：EP1042007B1
公开(公告)日：2004-08-11
申请号：EP98964242.6
申请日：1998-12-18
IPC分类号： A61L2/18 , C07C279/26 , A01N47/44
CPC分类号： A61L2/0088 , A01N47/44 , A61L12/141 , C07C279/26 , Y10S514/912
摘要： Aminobiguanides and the use of same as antimicrobial agents in pharmaceutical compositions are disclosed. The aminobiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting contact lenses.
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公开(公告)号：EP0757560B1
公开(公告)日：1999-12-22
申请号：EP96909529.8
申请日：1996-02-26
CPC分类号： A61K31/164 , A01N37/20 , A01N37/36 , A01N37/44 , A61L12/12 , Y10S514/84
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5.发明公开USE OF POLYETHYLENE OXIDE-CONTAINING POLYMERIC QUATERNARY AMMONIUM COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS 失效聚环氧乙烷的使用包含在药物制剂中·聚合的季铵化合物
公开(公告)号：EP0731714A1
公开(公告)日：1996-09-18
申请号：EP95932460.0
申请日：1995-09-19
发明人： PARK, Joonsup
CPC分类号： A01N33/12 , A61L12/145 , C08G65/33303 , Y10S514/839 , Y10S514/84
摘要： PEO-containing quaternary ammonium compounds have good broad spectrum antimicrobial activity. These compounds are useful in pharmaceutical compositions as preservatives and in contact lens care compositions as preservatives and/or disinfectants.
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6.发明授权USE OF POLYETHYLENE OXIDE-CONTAINING POLYMERIC QUATERNARY AMMONIUM COMPOUNDS IN PHARMACEUTICAL COMPOSITIONS 失效聚环氧乙烷的使用包含在药物制剂中·聚合的季铵化合物
公开(公告)号：EP0731714B1
公开(公告)日：2003-07-16
申请号：EP95932460.9
申请日：1995-09-19
发明人： PARK, Joonsup
CPC分类号： A01N33/12 , A61L12/145 , C08G65/33303 , Y10S514/839 , Y10S514/84
摘要： PEO-containing quaternary ammonium compounds have good broad spectrum antimicrobial activity. These compounds are useful in pharmaceutical compositions as preservatives and in contact lens care compositions as preservatives and/or disinfectants.
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7.发明授权
公开(公告)号：EP0904313B1
公开(公告)日：2001-11-21
申请号：EP96916921.8
申请日：1996-05-31
CPC分类号： C08G73/02 , A01N33/12 , A61K31/785 , A61L12/145 , C07B2200/09 , C07C29/17 , C07C29/62 , C08G73/0226 , C07C33/046 , C07C33/426
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8.发明公开AMINOBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS 有权AMINOBIGUANIDE及其用途隐形眼镜消毒保鲜药物制剂
公开(公告)号：EP1042007A2
公开(公告)日：2000-10-11
申请号：EP98964242.6
申请日：1998-12-18
IPC分类号： A61L2/18 , C07C279/26 , A01N47/44
CPC分类号： A61L2/0088 , A01N47/44 , A61L12/141 , C07C279/26 , Y10S514/912
摘要： Aminobiguanides and the use of same as antimicrobial agents in pharmaceutical compositions are disclosed. The aminobiguanides are useful in the preservation of pharmaceutical compositions, particularly ophthalmic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting contact lenses.
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9.发明公开
公开(公告)号：EP0904313A1
公开(公告)日：1999-03-31
申请号：EP96916921.0
申请日：1996-05-31
CPC分类号： C08G73/02 , A01N33/12 , A61K31/785 , A61L12/145 , C07B2200/09 , C07C29/17 , C07C29/62 , C08G73/0226 , C07C33/046 , C07C33/426
摘要： A process for preparing defined molecular weight polymers, particularly polyquaternary ammonium compounds, is disclosed. As the molecular weights of these compounds can be absolutely defined, rather than defined merely in terms of 'number average molecular weight', these compounds are particularly useful as identification standard for other polymers which are made using conventional polymerization processes. The polyquaternary ammonium compounds described are further suitable for use as antimicrobial agents, particularly in ophthalmic compositions.
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10.发明公开
公开(公告)号：EP1140805A1
公开(公告)日：2001-10-10
申请号：EP99966414.7
申请日：1999-12-17
IPC分类号： C07C279/28 , C08G73/00 , A61L12/14
CPC分类号： C08G73/00 , A61L12/142 , C07C279/28
摘要： Amido polybiguanides and their use as antimicrobial agents in pharmaceutical compositions are disclosed. A method of synthesis of amido polybiguanides is also disclosed. The amido polybiguanides are useful in the preservation of pharmaceutical compositions, particulary ophthalmic and otic pharmaceutical compositions and compositions for treating contact lenses. The compounds are especially useful for disinfecting contact lenses.
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