-
1.发明授权
公开(公告)号：EP2271670B1
公开(公告)日：2014-09-03
申请号：EP09719709.9
申请日：2009-03-13
申请人： ALLERGAN, INC.
发明人： FERNANDEZ-SALAS, Ester , WANG, Joanne , GARAY, Patton, E. , WONG, Lina, S. , HODGES, D., Dianne , AOKI, Kei, Roger
IPC分类号： C07K16/12 , G01N33/569
CPC分类号： C07K16/1282 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C12Q1/37 , G01N33/5014 , G01N33/566 , G01N33/6854
-
2.发明公开
公开(公告)号：EP2271670A1
公开(公告)日：2011-01-12
申请号：EP09719709.9
申请日：2009-03-13
申请人： Allergan, Inc.
发明人： FERNANDEZ-SALAS, Ester , WANG, Joanne , GARAY, Patton, E. , WONG, Lina, S. , HODGES, D., Dianne , AOKI, Kei, Roger
IPC分类号： C07K16/12 , G01N33/569
CPC分类号： C07K16/1282 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/92 , C12Q1/37 , G01N33/5014 , G01N33/566 , G01N33/6854
摘要： The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P
1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P
1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.-
3.发明公开
公开(公告)号：EP3630298A1
公开(公告)日：2020-04-08
申请号：EP18732563.4
申请日：2018-05-30
申请人： Allergan, Inc.
-
4.发明公开CELLS USEFUL FOR IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS 有权FÜRBOTULINUMTOXIN-SEROTYP-A-AKTIVITÄTSTESTSAUF IMMUNBASIS GEEIGNETE ZELLEN
公开(公告)号：EP2406371A1
公开(公告)日：2012-01-18
申请号：EP10709359.3
申请日：2010-03-12
申请人： Allergan, Inc.
CPC分类号： C12N5/0618 , C12N5/0693 , G01N33/5014
摘要： The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
摘要翻译： 本说明书公开了对BoNT / A中毒敏感的克隆细胞系，产生这种克隆细胞系的方法，以及使用这种克隆细胞系检测肉毒杆菌毒素血清型A活性的方法。
-
5.发明授权CELLS USEFUL FOR IMMUNO-BASED BOTULINUM TOXIN SEROTYPE A ACTIVITY ASSAYS 有权用于基于免疫的肉毒杆菌毒素血清型A活性测定的细胞
公开(公告)号：EP2406371B1
公开(公告)日：2018-05-09
申请号：EP10709359.3
申请日：2010-03-12
申请人： ALLERGAN, INC.
CPC分类号： C12N5/0618 , C12N5/0693 , G01N33/5014
摘要： The present specification discloses clonal cell lines susceptible to BoNT/A intoxication, methods of producing such clonal cell lines, and methods of detecting Botulinum toxin serotype A activity using such clonal cell lines.
-
6.发明公开Highly Sensitive Cell-Based Assay to Detect the Presence of Active Botulinum Neurotoxin Serotype-A 审中-公开HOCHSENSIBELER ZELLBASIERTER测定FÜRDEN NACHWEIS VON AKTIVEN BOTULINUM NEUROTOXIN SEROTYP A
公开(公告)号：EP2798077A2
公开(公告)日：2014-11-05
申请号：EP12816419.1
申请日：2012-12-28
申请人： ALLERGAN, INC. , Wang, Joanne , Dixit, Anuradha , Abel, Kenton B. , Gupta, Swati , Fernandez-Salas, Ester
IPC分类号： C12Q1/37
CPC分类号： G01N33/56911 , C12Q1/37 , G01N33/573 , G01N2333/33
摘要： The present specification discloses methods for detecting extremely low amounts of botulinum neurotoxin serotype A in samples, including complex matrices like blood, plasma, and serum.
摘要翻译： 本说明书公开了用于检测样品中极少量的肉毒杆菌神经毒素血清型A的方法，包括复合基质如血液，血浆和血清。
-
公开(公告)号：EP2406629B9
公开(公告)日：2014-03-26
申请号：EP10709360.1
申请日：2010-03-12
申请人： Allergan, Inc.
CPC分类号： G01N33/573 , C07K16/18 , C07K2317/34 , C07K2317/56 , C07K2317/92 , C12N9/50 , C12Q1/37 , C12Y304/24069 , G01N33/5014 , G01N33/5035 , G01N33/53 , G01N2333/33 , G01N2333/47 , G01N2333/952 , G01N2333/96425
摘要： The present specification discloses SNAP-25 immune response inducing compositions, methods of making a- SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the PI residue of the BoNT/A cleavage site scissile bond, ±-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing ±-re-targeted endopeptidase antibodies.
-
公开(公告)号：EP2406629B1
公开(公告)日：2013-09-18
申请号：EP10709360.1
申请日：2010-03-12
申请人： Allergan, Inc.
CPC分类号： G01N33/573 , C07K16/18 , C07K2317/34 , C07K2317/56 , C07K2317/92 , C12N9/50 , C12Q1/37 , C12Y304/24069 , G01N33/5014 , G01N33/5035 , G01N33/53 , G01N2333/33 , G01N2333/47 , G01N2333/952 , G01N2333/96425
摘要： The present specification discloses SNAP-25 immune response inducing compositions, methods of making a- SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the PI residue of the BoNT/A cleavage site scissile bond, ±-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing ±-re-targeted endopeptidase antibodies.
-
公开(公告)号：EP2406629A1
公开(公告)日：2012-01-18
申请号：EP10709360.1
申请日：2010-03-12
申请人： Allergan, Inc.
CPC分类号： G01N33/573 , C07K16/18 , C07K2317/34 , C07K2317/56 , C07K2317/92 , C12N9/50 , C12Q1/37 , C12Y304/24069 , G01N33/5014 , G01N33/5035 , G01N33/53 , G01N2333/33 , G01N2333/47 , G01N2333/952 , G01N2333/96425
摘要： The present specification discloses SNAP-25 immune response inducing compositions, methods of making a- SNAP-25 antibodies that selectively binds to an epitope comprising a SNAP-25 having a carboxyl-terminus at the PI residue of the BoNT/A cleavage site scissile bond, ±-SNAP-25 antibodies that selectively bind to an epitope comprising a SNAP-25 having a carboxyl-terminus at the P1 residue of the BoNT/A cleavage site scissile bond, methods of detecting retargeted endopeptidase activity, and methods of detecting neutralizing ±-re-targeted endopeptidase antibodies.
-
-
-
-
-
-
-
-
搜索结果
9 条记录 (耗时 0.033 秒)
