公开(公告)号：EP0792164B1

公开(公告)日：2004-01-21

申请号：EP95941351.9

申请日：1995-11-01

申请人： ALZA CORPORATION

发明人： GYORY, J.Richard ,  YIEH, Jane ,  HUNTINGTON, James A. ,  CORMIER, Michel

IPC分类号： A61K47/10 ,  A61K9/00

CPC分类号： A61N1/0412 ,  A61K9/0009 ,  A61N1/0428 ,  A61N1/30

公开(公告)号：EP0804155A1

公开(公告)日：1997-11-05

申请号：EP95925470.0

申请日：1995-06-29

申请人： ALZA CORPORATION

发明人： GYORY, J.Richard

IPC分类号： A61N1 ,  A61K9 ,  A61K47

CPC分类号： A61K9/0009

摘要： A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device (10) is also provided having a reservoir (16) comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.

公开(公告)号：EP0804155B1

公开(公告)日：2000-11-08

申请号：EP95925470.7

申请日：1995-06-29

申请人： ALZA CORPORATION

发明人： GYORY, J.Richard

IPC分类号： A61K9/00

CPC分类号： A61K9/0009

摘要： A composition comprises an agent to be delivered through a body surface and an electrotransport enhancer having a hydrophobic tail and a polar head of specific characteristics. An electrotransport delivery device is also provided having a reservoir comprising the agent to be delivered and the electrotransport enhancer of the invention. The electrotransport enhancers increase the electrotransport delivery rate of the agent through the surface while reducing the electrical resistance of the surface during electrotransport of the agent.

公开(公告)号：EP0792164A1

公开(公告)日：1997-09-03

申请号：EP95941351.0

申请日：1995-11-01

申请人： ALZA CORPORATION

发明人： GYORY, J.Richard ,  YIEH, Jane ,  HUNTINGTON, James A. ,  CORMIER, Michel

IPC分类号： A61K9 ,  A61K47 ,  A61N1

CPC分类号： A61N1/0412 ,  A61K9/0009 ,  A61N1/0428 ,  A61N1/30

摘要： An electrotransport composition comprises at least one C2-C4 lower alcohol, unsaturated derivatives thereof, or mixtures thereof, and at least one C8-C14 higher alcohol, unsaturated derivatives thereof, or mixtures thereof. An electrotransport device and a method of increasing transdermal electrotransport flux utilize the composition of the invention for delivering pharmaceutically-acceptable agents across a body surface such as skin.