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19 条记录 (耗时 0.016 秒)

    DOSAGE FORM FOR DELIVERY OF MULTIPLE DRUG FORMS
    7.
    发明公开
    DOSAGE FORM FOR DELIVERY OF MULTIPLE DRUG FORMS 审中-公开
    药物剂型FOR SUPPLY多种药物表格

    公开(公告)号：EP1750678A2

    公开(公告)日：2007-02-14

    申请号：EP05759174.5

    申请日：2005-05-20

    申请人： ALZA CORPORATION

    发明人： EDGREN, David, E. ,  HSU, Bih-Hsiung ,  LI, Shu

    IPC分类号： A61K9/20 ,  A61K9/28

    CPC分类号： A61K9/209 ,  A61K9/0004 ,  A61K9/2086

    摘要： Disclosed are controlled release dosage forms and related methods including: (a) a micronized or liquid base form of a drug; (b) either a pharmaceutically acceptable salt form of the drug or starting materials that are capable of reacting to form a pharmaceutically acceptable salt form of the drug; (c) an upper gastrointestinal system pharmaceutically acceptable salt form releasing structure; and (d) a colonic system base form releasing structure.

    VOLUME EFFICIENT CONTROLLED RELEASE DOSAGE FORM
    8.
    发明公开
    VOLUME EFFICIENT CONTROLLED RELEASE DOSAGE FORM 有权
    VOLUME节能药物剂型控释

    公开(公告)号：EP1499289A2

    公开(公告)日：2005-01-26

    申请号：EP03721484.8

    申请日：2003-03-28

    申请人： Alza Corporation

    发明人： WONG, Patrick, S.L. ,  JAO, Francisco ,  EDGREN, David, E. ,  SKLUZACEK, Robert, R. ,  LI, Shu, S.L.

    IPC分类号： A61K9/00

    CPC分类号： A61K9/0004

    摘要： The present invention includes a dosage form that facilitates the controlled release of an active agent at a desired release rate or release rate profile. In each embodiment, the dosage form of the present invention includes a bi-layer membrane system and an osmotic core. The bi-layer membrane system includes a semipermeable membrane and an osmosensitive membrane and forms an internal compartment that is occupied by the osmotic core. The osmotic core of the dosage form of the present invention includes and active agent composition and a light push layer. The dosage form of the present invention additionally includes a passageway that is formed through the bi-layer membrane system and permits expulsion of the active agent composition from the dosage form during operation. The bi-layer membrane system and the osmotic core of the dosage form of the present invention are formulated and formed to provide controlled release of the active agent included in the active agent composition of the osmotic core, while simultaneously facilitating increased loading of active agent within a dosage form of given dimension and increasing the delivery efficiency of such active agent relative to prior osmotic dosage forms including a push layer.

    OSMOTIC DOSAGE FORM COMPRISING FIRST AND SECOND COATS
    9.
    发明授权
    OSMOTIC DOSAGE FORM COMPRISING FIRST AND SECOND COATS 有权
    含有第一和第二涂层的渗透剂量形式

    公开(公告)号：EP1035834B1

    公开(公告)日：2002-04-17

    申请号：EP98959576.4

    申请日：1998-11-23

    申请人： ALZA CORPORATION

    发明人： EDGREN, David, E. ,  SKLUZACEK, Robert, R.

    IPC分类号： A61K9/00 ,  A61K9/28

    CPC分类号： A61K9/0004

    摘要： A dosage form comprising a composition comprising a drug surrounded by a first coat and a second coat with an exit for administering the drug to a patient; and a method of using the dosage form are disclosed for an indicated therapy.

    摘要翻译： 包含组合物的剂型，所述组合物包含被第一包衣和第二包衣包围的药物，所述第二包衣具有用于将所述药物给予患者的出口; 并公开了一种使用该剂型的方法。