利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

11 条记录 (耗时 0.013 秒)

    DOSAGE FORM PROVIDING TIME-VARYING PATTERNS OF DRUG DELIVERY
    2.
    发明公开
    DOSAGE FORM PROVIDING TIME-VARYING PATTERNS OF DRUG DELIVERY 审中-公开
    管理形式随时间变化的-RELEASE

    公开(公告)号：EP1492509A1

    公开(公告)日：2005-01-05

    申请号：EP02792484.4

    申请日：2002-12-18

    申请人： ALZA Corporation

    发明人： EDGREN, David, Emil ,  LI, Shu ,  WONG, Patrick, S., L.

    IPC分类号： A61K9/28 ,  A61K31/277 ,  A61K9/00

    CPC分类号： A61K9/0004 ,  A61K31/277

    摘要： The present invention provides a multi-release oral drug delivery system that initiates drug release following an initial drug-free release interval, after administration to a subject, and a second drug-free release period before release of another dose of drug. The system has (1) inner compartments enclosed within a semipermeable membrane, and (2) a drug coating on the exterior of the semipermeable membrane surrounded by a microporous membrane, which microporous membrane is permeable to fluid and drug. The drug coating is released after the initial drug-free release interval. An inner compartment drug is released after a second drug-free release interval provided by a drug-free inner compartment.

    DOSAGE FORM FOR DELIVERY OF MULTIPLE DRUG FORMS
    3.
    发明公开
    DOSAGE FORM FOR DELIVERY OF MULTIPLE DRUG FORMS 审中-公开
    药物剂型FOR SUPPLY多种药物表格

    公开(公告)号：EP1750678A2

    公开(公告)日：2007-02-14

    申请号：EP05759174.5

    申请日：2005-05-20

    申请人： ALZA CORPORATION

    发明人： EDGREN, David, E. ,  HSU, Bih-Hsiung ,  LI, Shu

    IPC分类号： A61K9/20 ,  A61K9/28

    CPC分类号： A61K9/209 ,  A61K9/0004 ,  A61K9/2086

    摘要： Disclosed are controlled release dosage forms and related methods including: (a) a micronized or liquid base form of a drug; (b) either a pharmaceutically acceptable salt form of the drug or starting materials that are capable of reacting to form a pharmaceutically acceptable salt form of the drug; (c) an upper gastrointestinal system pharmaceutically acceptable salt form releasing structure; and (d) a colonic system base form releasing structure.

    ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE
    9.
    发明公开
    ORAL OSMOTIC DOSAGE FORM HAVING A HIGH FLUX MEMBRANE 有权
    用芦苇高密度流动口服渗透药物剂型

    公开(公告)号：EP1858492A2

    公开(公告)日：2007-11-28

    申请号：EP06734068.7

    申请日：2006-01-27

    申请人： Alza Corporation

    发明人： EDGREN, David, E. ,  BHATTI, Gurdish, K. ,  LI, Shu ,  SKLUZACEK, Robert

    IPC分类号： A61K9/28

    CPC分类号： A61K9/0004

    摘要： Disclosed are oral osmotic dosage forms and methods wherein a semipermeable membrane of the oral osmotic dosage form includes from about 23 wt% to about 50 wt% of a flux enhancer and from about 0.01 wt% to about 5 wt% of antioxidant, based on the total dry weight of the semi-permeable membrane. Such compositions provide high flux membranes with improved mechanical and transport stability during storage on the shelf.