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1.发明公开Immunologic enhancement of the somatogenic effect of somatotropin with an antibody 失效Immunologische Vermehrung des somatogenischen Effekts von somatotropin mit einemAntikörper。
公开(公告)号：EP0458072A1
公开(公告)日：1991-11-27
申请号：EP91106423.6
申请日：1991-04-22
IPC分类号： C12P21/08 , A61K39/395
CPC分类号： C07K16/26 , A61K39/395 , A61K2300/00
摘要： The present invention is directed to antibodies, in particular monoclonal antibodies, of porcine somatotropin (pST). When these antibodies are administered together with pST, the growth of vertebrates is greater than that achieved with the administration of pST alone. The invention is also directed to an increase in the growth of vertebrates which persists over long periods when an antibody to a somatotropin is administered together with such somatotropin.
摘要翻译： 本发明涉及猪生长激素（pST）的抗体，特别是单克隆抗体。 当这些抗体与pST一起施用时，脊椎动物的生长大于单独施用pST所达到的生长。 本发明还涉及当与生长激素一起施用生长激素的抗体时长时间持续的脊椎动物的生长的增加。
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2.发明授权Immunologic enhancement of the somatogenic effect of somatotropin with an antibody 失效与抗体生长激素的somatogenischen影响免疫增加。
公开(公告)号：EP0458072B1
公开(公告)日：1995-09-13
申请号：EP91106423.6
申请日：1991-04-22
IPC分类号： C12P21/08 , A61K39/395
CPC分类号： C07K16/26 , A61K39/395 , A61K2300/00
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3.发明授权An antibody to the carboxyl terminus peptide of rat somatotropin binding protein 失效抗体在大鼠生长激素结合蛋白的羧基末端肽
公开(公告)号：EP0439797B1
公开(公告)日：1998-03-04
申请号：EP90125021.7
申请日：1990-12-20
发明人： Baumbach, William Robert , Wang, Bosco Shang , Sadeghi, Homayoun , Logan, John Steele , Hart, Ian C.
IPC分类号： C07K14/72 , C07K16/28 , A61K38/27 , G01N33/577 , G01N33/74
CPC分类号： C07K16/2869 , A61K38/00
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4.发明公开Antibodies specifically recognizing somatotropin binding protein 失效Antikörper，die spezifisch mit somatotropin-Bindungsprotein reagieren。
公开(公告)号：EP0439797A1
公开(公告)日：1991-08-07
申请号：EP90125021.7
申请日：1990-12-20
发明人： Baumbach, William Robert , Wang, Bosco Shang , Sadeghi, Homayoun , Logan, John Steele , Hart, Ian C.
IPC分类号： C12P21/08 , C12N5/20 , G01N33/577 , G01N33/74 , A61K39/395
CPC分类号： C07K16/2869 , A61K38/00
摘要： The present invention is directed to antibodies, in particular monoclonal antibodies, which specifically react with somatotropin binding proteins of animals, but not with the corresponding somatotropin receptors. The antibodies may be used alone to enhance the growth of animals, or may be used together with somatotropin to potentiate the effect of somatotropin in animals. The antibodies may also be used to assay the level of somatotropin binding protein of animals.
摘要翻译： 本发明涉及与动物的生长激素结合蛋白特异性反应但不与相应的生长激素受体特异性反应的抗体，特别是单克隆抗体。 抗体可以单独使用以增强动物的生长，或者可以与生长激素一起使用以增强动物体内生长激素的作用。 抗体也可用于测定动物生长激素结合蛋白的水平。
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5.发明公开Fragments of porcine somatotropin and antibodies thereto enhancing porcine somatotropin activity 失效猪生长激素和其抗体片段，这增加了猪生长激素活性。
公开(公告)号：EP0429788A2
公开(公告)日：1991-06-05
申请号：EP90118001.8
申请日：1990-09-19
CPC分类号： C07K16/26 , A61K38/00 , C07K14/61 , C07K2317/34
摘要： This invention is directed to peptide fragments of porcine somatotropin (pST) which are used to generate epitope-specific anti-pST antibodies. When such antibodies are administered with pST to warm-blooded animals, the growth enhancing activity of pST is potentiated.
摘要翻译： 本发明涉及肽，其被用于产生表位特异性的抗抗体的pST猪生长激素（PST）的片段。 当寻求抗体在使用PST给予温血动物，PST的增长增强活性加强。
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