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公开(公告)号：EP0492179A3
公开(公告)日：1992-12-09
申请号：EP91120566.4
申请日：1991-11-29
CPC分类号： C07K14/465 , A61K38/00 , C07K14/72
摘要： The present invention relates to novel DNA sequences encoding an avian growth hormone receptor and growth hormone binding protein, as well as the purified proteins per se . The invention also relates to methods for increasing growth of domesticated fowl, such as chickens, turkeys, ducks or geese, by manipulation of the expression of the growth hormone receptor gene.
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2.发明公开Antibodies specifically recognizing somatotropin binding protein 失效Antikörper，die spezifisch mit somatotropin-Bindungsprotein reagieren。
公开(公告)号：EP0439797A1
公开(公告)日：1991-08-07
申请号：EP90125021.7
申请日：1990-12-20
发明人： Baumbach, William Robert , Wang, Bosco Shang , Sadeghi, Homayoun , Logan, John Steele , Hart, Ian C.
IPC分类号： C12P21/08 , C12N5/20 , G01N33/577 , G01N33/74 , A61K39/395
CPC分类号： C07K16/2869 , A61K38/00
摘要： The present invention is directed to antibodies, in particular monoclonal antibodies, which specifically react with somatotropin binding proteins of animals, but not with the corresponding somatotropin receptors. The antibodies may be used alone to enhance the growth of animals, or may be used together with somatotropin to potentiate the effect of somatotropin in animals. The antibodies may also be used to assay the level of somatotropin binding protein of animals.
摘要翻译： 本发明涉及与动物的生长激素结合蛋白特异性反应但不与相应的生长激素受体特异性反应的抗体，特别是单克隆抗体。 抗体可以单独使用以增强动物的生长，或者可以与生长激素一起使用以增强动物体内生长激素的作用。 抗体也可用于测定动物生长激素结合蛋白的水平。
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3.发明公开DNA 5' to an untranslated region upstream of a gene encoding a growth hormone receptor. Use as a sex promoter 失效编码生长激素受体的基因的非翻译区上述DNA 5”。 在确定性别使用的一个因素。
公开(公告)号：EP0553428A2
公开(公告)日：1993-08-04
申请号：EP92120158.8
申请日：1992-12-11
CPC分类号： A01K67/0275 , A01K2217/05 , A61K38/00 , C07K14/71
摘要： The present invention relates to an isolated nucleic acid sequence which, as a promoter, is regulated in a developmental- and sex-specific manner. The sequence is useful in DNA constructs, in combination with a gene of interest, to achieve developmental and sex-specific expression of the gene in transgenic animals.
摘要翻译： 本发明涉及到其中，作为启动子，在一个developmental-和性别特异性方式调节分离的核酸序列。 该序列是在DNA构建体是有用的，结合的感兴趣的基因，实现在转基因动物的基因的发育和性别 - 特异性表达。
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公开(公告)号：EP0972448A2
公开(公告)日：2000-01-19
申请号：EP99305410.5
申请日：1999-07-07
IPC分类号： A01N43/56
CPC分类号： A01N43/56
摘要： The present invention provides a method to control parasitic mites on beneficial insects, such as honeybees, via the application of a parasiticidally effective amount of tebufenpyrad.
摘要翻译： 本发明提供了通过施用杀寄生物有效量的特布芬吡拉来控制有益昆虫如蜜蜂上的寄生螨的方法。
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公开(公告)号：EP0863156A1
公开(公告)日：1998-09-09
申请号：EP98301654.4
申请日：1998-03-05
IPC分类号： C07K14/655 , C07K7/06 , C07K14/60 , A61K38/08 , A61K38/31
CPC分类号： C07K14/60 , A61K38/00 , C07K14/6555
摘要： The present invention provides peptides having pure somatostatin antagonist activity. Also provided are methods for increasing the release of growth hormone, insulin, glucagon and gastric enzymes in mammals and a method for the enhancement of immune function and growth in mammals.
摘要翻译： 本发明提供具有纯生长抑素拮抗剂活性的肽。 还提供了增加哺乳动物中生长激素，胰岛素，胰高血糖素和胃酶的释放的方法以及用于增强哺乳动物的免疫功能和生长的方法。
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6.发明公开Avian growth hormone receptor and binding protein 失效ReveptorfürVogelwachstumshormone und Bindungsprotein。
公开(公告)号：EP0492179A2
公开(公告)日：1992-07-01
申请号：EP91120566.4
申请日：1991-11-29
CPC分类号： C07K14/465 , A61K38/00 , C07K14/72
摘要： The present invention relates to novel DNA sequences encoding an avian growth hormone receptor and growth hormone binding protein, as well as the purified proteins per se . The invention also relates to methods for increasing growth of domesticated fowl, such as chickens, turkeys, ducks or geese, by manipulation of the expression of the growth hormone receptor gene.
摘要翻译： 本发明涉及编码禽类生长激素受体和生长激素结合蛋白的新型DNA序列，以及纯化的蛋白质本身。 本发明还涉及通过操纵生长激素受体基因的表达来增加家禽如鸡，火鸡，鸭或鹅的生长的方法。
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8.发明授权An antibody to the carboxyl terminus peptide of rat somatotropin binding protein 失效抗体在大鼠生长激素结合蛋白的羧基末端肽
公开(公告)号：EP0439797B1
公开(公告)日：1998-03-04
申请号：EP90125021.7
申请日：1990-12-20
发明人： Baumbach, William Robert , Wang, Bosco Shang , Sadeghi, Homayoun , Logan, John Steele , Hart, Ian C.
IPC分类号： C07K14/72 , C07K16/28 , A61K38/27 , G01N33/577 , G01N33/74
CPC分类号： C07K16/2869 , A61K38/00
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9.发明公开DNA 5' to an untranslated region upstream of a gene encoding a growth hormone receptor. Use as a sex promoter 失效DNA 5'至编码生长激素受体的基因的不间断区域上游。 用作SEX PROMOTER
公开(公告)号：EP0553428A3
公开(公告)日：1994-07-06
申请号：EP92120158.8
申请日：1992-12-11
CPC分类号： A01K67/0275 , A01K2217/05 , A61K38/00 , C07K14/71
摘要： The present invention relates to an isolated nucleic acid sequence which, as a promoter, is regulated in a developmental- and sex-specific manner. The sequence is useful in DNA constructs, in combination with a gene of interest, to achieve developmental and sex-specific expression of the gene in transgenic animals.
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公开(公告)号：EP0383205A1
公开(公告)日：1990-08-22
申请号：EP90102552.8
申请日：1990-02-09
CPC分类号： C07K16/2869 , A61K38/00 , C07K14/72
摘要： The present invention relates to the novel protein and DNA of serum somatotropin binding protein. The novel protein of the present invention uniquely contains a 17 amino acid "tail" on the carboxy terminal of the protein, produced by alternative splicing of RNA for the somatotropin receptor. The present invention also includes a method for identifying the serum somatotropin binding protein separate from the somatotropin receptor protein. This novel protein is useful in altering and affecting growth characteristics of animals.
摘要翻译： 本发明涉及血清生长激素结合蛋白的新型蛋白质和DNA。 本发明的新型蛋白质在蛋白质的羧基末端唯一地含有17个氨基酸的“尾”，通过用于生长激素受体的RNA的选择性剪接产生。 本发明还包括鉴定与生长激素受体蛋白分离的血清生长激素结合蛋白的方法。 这种新型蛋白质可用于改变和影响动物的生长特性。
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