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公开(公告)号：EP0890640A2
公开(公告)日：1999-01-13
申请号：EP98113221.0
申请日：1994-01-27
申请人： AMGEN INC.
发明人： Osslund, Thimothy
CPC分类号： C07K1/00 , A61K38/00 , C07K14/535 , C07K2299/00 , C07K2319/00 , Y02A90/26
摘要： Provided herein are granulocyte colony stimulating factor ("G-CSF") analogs, compositions containing such analogs, and related compositions. In another aspect, provided herein are nucleic acids encoding the present analogs or related nucleic acids, related host cells and vectors. In yet another aspect, provided herein are computer programs and apparatuses for expressing the three dimensional structure of G-CSF and analogs thereof. In another aspect, provided herein are methods for rationally designing G-CSF analogs and related compositions. In yet another aspect, provided herein are methods for treatment using the present G-CSF analogs.
摘要翻译： 本文提供了粒细胞集落刺激因子（“G-CSF”）类似物，含有此类类似物的组合物和相关组合物。 在另一方面，本文提供了编码本发明的类似物或相关核酸，相关宿主细胞和载体的核酸。 在另一方面，本文提供了用于表达G-CSF及其类似物的三维结构的计算机程序和装置。 在另一方面，本文提供了合理设计G-CSF类似物和相关组合物的方法。 在另一方面，本文提供了使用本发明G-CSF类似物进行治疗的方法。
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公开(公告)号：EP0890640A3
公开(公告)日：1999-03-24
申请号：EP98113221.0
申请日：1994-01-27
申请人： AMGEN INC.
发明人： Osslund, Thimothy
CPC分类号： C07K1/00 , A61K38/00 , C07K14/535 , C07K2299/00 , C07K2319/00 , Y02A90/26
摘要： Provided herein are granulocyte colony stimulating factor ("G-CSF") analogs, compositions containing such analogs, and related compositions. In another aspect, provided herein are nucleic acids encoding the present analogs or related nucleic acids, related host cells and vectors. In yet another aspect, provided herein are computer programs and apparatuses for expressing the three dimensional structure of G-CSF and analogs thereof. In another aspect, provided herein are methods for rationally designing G-CSF analogs and related compositions. In yet another aspect, provided herein are methods for treatment using the present G-CSF analogs.
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