公开(公告)号：EP1844426A4

公开(公告)日：2016-09-07

申请号：EP06720094

申请日：2006-02-01

申请人： AMNIS CORP

发明人： ORTYN WILLIAM ,  BASIJI DAVID ,  GEORGE THADDEOUS ,  MORRISSEY PHILIP ,  HALL BRIAN ,  PERRY DAVID ,  ZIMMERMAN CATHLEEN

IPC分类号： G06K9/00

CPC分类号： G06K9/00127 ,  G01N15/147 ,  G01N15/1475 ,  G01N2015/1497

摘要： Multimodal/multispectral images of a population of cells are simultaneously collected. Photometric and/or morphometric features identifiable in the images are used to separate the population of cells into a plurality of subpopulations. Where the population of cells includes diseased cells and healthy cells, the images can be separated into a healthy subpopulation, and a diseased subpopulation. Where the population of cells does not include diseased cells, one or more ratios of different cell types in patients not having a disease condition can be compared to the corresponding ratios in patients having the disease condition, enabling the disease condition to be detected. For example, blood cells can be separated into different types based on their images, and an increase in the number of lymphocytes, a phenomenon associated with chronic lymphocytic leukemia, can readily be detected.