专利检索 ap:("AMR Technology, Inc." OR "Bristol-Myers Squibb Company") AND inv:"MANNING, David, D." 第 1 页

1.

发明公开
ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROBENZAZEPINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN 有权
标题翻译：芳基和杂-tetrahydrobenzazepines并用它来恢复LOCKING去甲肾上腺素，多巴胺和血清素

公开(公告)号：EP1904069A2

公开(公告)日：2008-04-02

申请号：EP06787476.8

申请日：2006-07-17

申请人： AMR Technology, Inc. , Bristol-Myers Squibb Company

发明人： MOLINO, Bruce, F. , LIU, Shuang , SAMBANDAM, Aruna , GUZZO, Peter, R. , HU, Min , ZHA, Congxiang , NACRO, Kassoum , MANNING, David, D. , ISHERWOOD, Matthew, L. , FLEMING, Kristen, N. , CUI, Wenge , OLSON, Richard, E.

IPC分类号： A61K31/55 , C07D487/02 , C07D403/02

CPC分类号： C07D223/16 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D471/04 , C07D487/04

摘要： The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II) where the carbon atom designated * is in the R or S configuration, and the substituents X and R1-R9 are as defined herein.

2.

发明授权
ARYL-AND HETEROARYL-SUBSTITUTED TETRAHYDROBENZAZEPINES AND USE THEREOF TO BLOCK REUPTAKE OF NOREPINEPHRINE, DOPAMINE, AND SEROTONIN 有权

公开(公告)号：EP1904069B1

公开(公告)日：2018-06-13

申请号：EP06787476.8

申请日：2006-07-17

申请人： Albany Molecular Research, Inc. , Bristol-Myers Squibb Company

发明人： MOLINO, Bruce, F. , LIU, Shuang , SAMBANDAM, Aruna , GUZZO, Peter, R. , HU, Min , ZHA, Congxiang , NACRO, Kassoum , MANNING, David, D. , ISHERWOOD, Matthew, L. , FLEMING, Kristen, N. , CUI, Wenge , OLSON, Richard, E.

IPC分类号： A61P25/00 , A61K31/55 , C07D223/16

CPC分类号： C07D223/16 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/14 , C07D405/14 , C07D409/04 , C07D409/14 , C07D413/04 , C07D413/14 , C07D471/04 , C07D487/04

摘要： The compounds of the present invention are represented by the following aryl- and heteroaryl-substituted tetrahydrobenzazepine and dihydrobenzazapine derivatives having formulae I(A-E) and formula (II): where the carbon atom designated * is in the R or S configuration, and the substituents X and R1-R9 are as defined herein.