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公开(公告)号：EP3222289A4
公开(公告)日：2018-07-04
申请号：EP15861370
申请日：2015-11-20
CPC分类号： A61K39/292 , A61K39/0008 , A61K2039/53 , A61K2039/545 , A61K2039/70 , C12N7/00 , C12N2730/10134
摘要： The present invention provides a combination preparation for inducing a specific immune response to an antigenic peptide, which contains (I) the antigenic peptide, and (II) an expression vector encoding a chimeric hepatitis B virus core antigen polypeptide, into which the antigenic peptide has been inserted or added, wherein said antigenic peptide is inserted in a region of amino acid residues 74 - 87 or 130 - 138 of the hepatitis B virus core antigen polypeptide, or added to the N-terminal or C-terminal of the hepatitis B virus core antigen polypeptide, wherein the antigenic peptide of (I) and the expression vector of (II) are substantially simultaneously administered to a subject.
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2.发明公开DNA VACCINE CONTAINING VEGF-SPECIFIC EPITOPE AND/OR ANGIOPOIETIN-2-SPECIFIC EPITOPE 审中-公开DNA疫苗含VEGF-特异性表位和/或血管生成素-2特异性表位
公开(公告)号：EP2891497A4
公开(公告)日：2016-05-04
申请号：EP13832772
申请日：2013-08-28
申请人： UNIV OSAKA , ANGES MG INC
CPC分类号： A61K39/0011 , A61K2039/5256 , A61K2039/53 , A61K2039/545 , C12N7/00 , C12N2730/10134 , C12N2730/10143
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公开(公告)号：EP2698164A4
公开(公告)日：2015-01-21
申请号：EP12771621
申请日：2012-04-13
申请人： UNIV OSAKA , ANGES MG INC
IPC分类号： A61K39/00 , A61K35/76 , A61K39/12 , A61K39/29 , A61K48/00 , A61P3/06 , A61P9/12 , C07K14/02 , C07K14/47 , C07K14/575 , C12N15/09
CPC分类号： A61K39/292 , A61K39/0005 , A61K2039/53 , C07K14/575 , C07K2319/00 , C12N2730/10143 , C12N2770/32434
摘要： The present invention provides a therapeutic or improving agent for a lifestyle-related disease, containing an expression vector encoding a chimeric Hepatitis B virus core antigen polypeptide inserted with an amino acid sequence containing a specific epitope of the lifestyle-related disease-related factor, wherein the amino acid sequence containing the specific epitope is inserted between the amino acid residues 80 and 81 of the hepatitis B virus core antigen polypeptide.
摘要翻译： 本发明提供了一种用于生活方式相关疾病的治疗或改善剂，其含有编码嵌入式乙型肝炎病毒核心抗原多肽的表达载体，所述嵌合型乙型肝炎病毒核心抗原多肽插入含有与生活方式相关疾病相关因子的特异性表位的氨基酸序列，其中 将含有特异性表位的氨基酸序列插入到乙型肝炎病毒核心抗原多肽的氨基酸残基80和81之间。
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公开(公告)号：EP1911459A4
公开(公告)日：2009-09-30
申请号：EP06781920
申请日：2006-07-28
申请人： ANGES MG INC
CPC分类号： A61K38/1833 , A61K48/00 , A61K48/0016 , A61K48/0075 , C07K14/4753 , C12Q1/025 , G01N33/6872 , G01N2500/04
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5.发明公开THERAPEUTIC AGENT FOR PERIODONTAL DISEASE AND ALVEOLAR BONE LOSS DUE TO SURGERY 审中-公开治疗剂AGAINST牙周病牙槽骨丧失手术
公开(公告)号：EP2127681A4
公开(公告)日：2011-10-12
申请号：EP08711312
申请日：2008-02-15
申请人： ANGES MG INC
CPC分类号： A61K9/0063 , A61K31/713 , A61K48/00 , C12N15/113 , C12N2310/13
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公开(公告)号：EP1839664A4
公开(公告)日：2009-12-23
申请号：EP05816428
申请日：2005-12-15
申请人： ANGES MG INC
IPC分类号： A61K31/7088 , A61K48/00 , A61P1/02 , A61P19/00 , A61P19/02 , A61P19/08 , A61P19/10 , A61P29/00 , A61P35/00
CPC分类号： C12N15/113 , C12N2310/13
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7.发明公开DRUG ELUTION-TYPE CATHETER AND METHOD FOR MANUFACTURING THE DRUG ELUTION-TYPE CATHETER 审中-公开导管释放活性和方法用于生产导管-RELEASE
公开(公告)号：EP2251050A4
公开(公告)日：2013-08-14
申请号：EP09720078
申请日：2009-03-12
申请人： ANGES MG INC , MEDIKIT CO LTD , HOSOKAWA MICRON KK
发明人： MORISHITA RYUICHI , NAKAGAMI HIRONORI , MIYAKE TAKASHI , MITAMURA MAKOTO , NAKAJIMA HIROAKI , MATSUDA HIROAKI , SUIZU NAO , KAWANO YOSHIHUMI , TAKAGI KUNIHIKO , TSUJIMOTO HIROYUKI , TSUKADA YUSUKE , HARA KAORI , BANDO YOHEI
CPC分类号： A61L29/085 , A61L29/16 , A61L2300/258 , A61L2300/624 , A61L2400/12 , A61M25/0045 , A61M25/10 , A61M25/1027 , A61M25/104 , A61M2025/0057 , A61M2025/1031 , A61M2025/105 , A61M2025/1075 , A61M2025/1086
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公开(公告)号：EP1884240A4
公开(公告)日：2008-08-27
申请号：EP06732194
申请日：2006-04-21
申请人： DAIICHI SANKYO CO LTD , UNIV OSAKA
IPC分类号： A61K31/4178 , A61K31/4164 , A61P1/02 , A61P5/18 , A61P17/00 , A61P19/02 , A61P19/08 , A61P19/10 , A61P29/00 , A61P35/00 , C07D403/10
CPC分类号： C07D403/12 , A61K31/4164 , A61K31/4178 , C07D233/90 , C07D403/10 , C07D405/12 , C07D405/14
摘要： It is intended to provide a pharmaceutical for prevention or treatment of bone metabolic diseases comprising an angiotensin II receptor antagonist as an active ingredient. A preventive agent or therapeutic agent for bone metabolic diseases comprises a compound having the general formula (I): (I) [wherein, R1: a C1-C4 alkyl group; R2, R3: a hydrogen atom or a C1-C4 alkyl group; R4: a hydrogen atom or a C1-C4 alkyl group; R5: a hydrogen atom, a C1-C4 alkyl group, a C2-C5 alkanoyloxymethyl or 1-(C2-C5 alkanoyloxy)ethyl group, a C1-C4 alkoxycarbonyloxymethyl or 1-(C1-C4 alkoxycarbonyloxy)ethyl group, a (5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl group, a (5-phenyl-2-oxo-1,3-dioxolen-4-yl)methyl group or a phthalidyl group; R6: a carboxy group or a tetrazole-5-yl group], a pharmacologically acceptable salt thereof, or a pharmacologically acceptable ester thereof as an active ingredient.
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公开(公告)号：EP3088000A4
公开(公告)日：2017-08-09
申请号：EP14873679
申请日：2014-12-26
申请人： UNIV OSAKA
IPC分类号： A61K39/00 , A61K39/395 , A61K48/00 , A61P1/04 , A61P17/06 , A61P19/02 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/02 , A61P37/08 , C07K16/24
CPC分类号： C07K16/244 , A61K39/0005 , C07K2317/34 , C07K2317/76
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公开(公告)号：EP3199543A4
公开(公告)日：2018-04-25
申请号：EP15844602
申请日：2015-09-25
申请人： UNIV OSAKA
摘要： An object of the present invention is to provide a novel peptide and a novel immunostimulant or hair grower containing the peptide as an active ingredient. The present invention provides a peptide of 23 or less amino acids comprising the amino acid sequence LHRLKRLRKRL (SEQ ID NO: 1), preferably the amino acid sequence LHRLKRLRKRLK (SEQ ID NO: 9), and also provides an immunostimulant containing the peptide, a vaccine adjuvant containing the peptide, a vaccine composition containing the peptide, and a hair grower containing the peptide.
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