公开(公告)号：EP0700438B1

公开(公告)日：2005-02-09

申请号：EP94920679.1

申请日：1994-05-20

申请人： ARCH DEVELOPMENT CORPORATION

发明人： BELL, Graeme, I. ,  REISINE, Terry ,  YASUDA, Kazuki

IPC分类号： C07K14/705 ,  C12N15/12 ,  C12N15/62 ,  C12N5/10 ,  G01N33/68 ,  C12Q1/68 ,  A61K38/17 ,  C07K16/28

CPC分类号： C07K14/705 ,  A61K38/00 ,  C07K2319/00 ,  C07K2319/033 ,  C07K2319/32

摘要： The invention relates generally to compositions of and methods for obtaining opioid receptor polypeptides. The invention relates as well to polynucleotides encoding opioid receptor polypeptides, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant opioid receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of at least three different opioid receptor polypeptides. The invention includes as well methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with opioid receptor polypeptides for use in diagnostic, drug design and therapeutic applications.

公开(公告)号：EP0700438A1

公开(公告)日：1996-03-13

申请号：EP94920679.0

申请日：1994-05-20

申请人： ARCH DEVELOPMENT CORPORATION

发明人： BELL, Graeme, I. ,  REISINE, Terry ,  YASUDA, Kazuki

IPC分类号： G01N33 ,  A61K38 ,  A61K39 ,  A61P1 ,  A61P5 ,  A61P9 ,  A61P11 ,  A61P25 ,  A61P37 ,  A61P43 ,  C07H21 ,  C07K14 ,  C07K16 ,  C07K19 ,  C12N1 ,  C12N5 ,  C12N15 ,  C12P21 ,  C12Q1 ,  C12R1

CPC分类号： C07K14/705 ,  A61K38/00 ,  C07K2319/00 ,  C07K2319/033 ,  C07K2319/32

摘要： The invention relates generally to compositions of and methods for obtaining opioid receptor polypeptides. The invention relates as well to polynucleotides encoding opioid receptor polypeptides, the recombinant vectors carrying those sequences, the recombinant host cells including either the sequences or vectors, and recombinant opioid receptor polypeptides. By way of example, the invention discloses the cloning and functional expression of at least three different opioid receptor polypeptides. The invention includes as well methods for using the isolated, recombinant receptor polypeptides in assays designed to select and improve substances capable of interacting with opioid receptor polypeptides for use in diagnostic, drug design and therapeutic applications.