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公开(公告)号：EP0904094A1
公开(公告)日：1999-03-31
申请号：EP97918682.0
申请日：1997-04-17
CPC分类号： C07K14/575 , A61K38/00
摘要： A method for promoting bone growth in a patient (e.g., a mammal such as a human), said method including the step of administering a therapeutically effective amount of adrenomedullin or an adrenomedullin agonist to said patient.
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2.发明公开TREATMENT OF BONE DISORDERS WITH ADRENOMEDULLIN OR ADRENOMEDULLIN AGONISTS 审中-公开治骨疾病BY或肾上腺髓质ADRENOMEDULLINAGONISTEN的
公开(公告)号：EP1173470A1
公开(公告)日：2002-01-23
申请号：EP00911518.9
申请日：2000-03-29
IPC分类号： C07K7/06 , C07K7/08 , C07K14/575 , A61K38/08 , A61K38/10 , A61K38/22 , A61P19/08 , A61P19/10
CPC分类号： C07K14/575 , A61K38/00
摘要： A method for promoting bone growth in a patient (e.g., a mammal such as a human) said method including the step of administering a therapeutically effective amount of adrenomedullin or an adrenomedullin agonist to said patient.
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公开(公告)号：EP0904094B1
公开(公告)日：2005-10-12
申请号：EP97918682.2
申请日：1997-04-17
CPC分类号： C07K14/575 , A61K38/00
摘要： A method for promoting bone growth in a patient (e.g., a mammal such as a human), said method including the step of administering a therapeutically effective amount of adrenomedullin or an adrenomedullin agonist to said patient.
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公开(公告)号：EP1937298A1
公开(公告)日：2008-07-02
申请号：EP06812838.8
申请日：2006-10-16
CPC分类号： A61K38/40
摘要： The present invention relates to use of at least one lactoferrin fragment or a lactoferrin hydrolysate or a mixture thereof for stimulating skeletal growth, inhibiting bone resorption, stimulating chondrocyte proliferation, stimulating osteoblast proliferation, inhibiting osteoclast development or treating or preventing a skeletal, joint or cartilage disorder.
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5.发明授权Use of amylin, adrenomedullin and analogues thereof for treating cartilage defects 有权胰淀素，肾上腺髓质素的使用和其在软骨缺损的治疗类似物
公开(公告)号：EP1027027B1
公开(公告)日：2006-12-20
申请号：EP98946738.6
申请日：1998-09-25
CPC分类号： C12N5/0655 , A61K38/00 , C07K14/575 , C12N2500/38 , C12N2501/34 , C12N2501/998 , Y10S530/84
摘要： This invention is directed to new therapeutic uses which involve the stimulation of chondrocyte proliferation. More particularly, it is directed to the use of amylin and adrenomedullin as agents which stimulate chondrocyte proliferation and which therefore have utility in the treatment of cartilage disorders and/or cartilage mediated bone growth.
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公开(公告)号：EP1027027A2
公开(公告)日：2000-08-16
申请号：EP98946738.6
申请日：1998-09-25
IPC分类号： A61K6/00
CPC分类号： C12N5/0655 , A61K38/00 , C07K14/575 , C12N2500/38 , C12N2501/34 , C12N2501/998 , Y10S530/84
摘要： This invention is directed to new therapeutic uses which involve the stimulation of chondrocyte proliferation. More particularly, it is directed to the use of amylin and adrenomedullin as agents which stimulate chondrocyte proliferation and which therefore have utility in the treatment of cartilage disorders and/or cartilage mediated bone growth.
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