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公开(公告)号：EP3200881A1
公开(公告)日：2017-08-09
申请号：EP14903305.2
申请日：2014-09-30
申请人： Avon Products, Inc.
发明人： HU, Hong , YIM, Sunghan , SANTHANAM, Uma , LYGA, John W.
CPC分类号： A61K8/49 , A61K8/06 , A61K8/062 , A61K8/064 , A61K8/342 , A61K8/347 , A61K8/36 , A61K8/46 , A61K8/4926 , A61K8/675 , A61K2800/42 , A61K2800/48 , A61K2800/522 , A61K2800/524 , A61K2800/54 , A61Q19/02
摘要： Embodiments of the invention are generally directed to compositions useful for reducing pigmentation in the skin. The composition may further include other depigmenting agents such as nicotinamide and its melanasome transfer-inhibiting derivatives, 3,3′-thiodipropanoic acid and its tyrosinase-inhibiting derivatives, or resorcinol and its tyrosinase-inhibiting derivatives, in a topically acceptable vehicle.
摘要翻译： 本发明的实施方案通常涉及用于减少皮肤色素沉着的组合物。 在局部可接受的载体中，所述组合物可进一步包含其它脱色剂，例如烟酰胺及其黑素酶体转移抑制衍生物，3,3'-硫代二丙酸及其酪氨酸酶抑制衍生物或间苯二酚及其酪氨酸酶抑制衍生物。
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公开(公告)号：EP3200752A1
公开(公告)日：2017-08-09
申请号：EP14903380.5
申请日：2014-09-30
申请人： Avon Products, Inc.
发明人： HU, Hong , YIM, Sunghan , SANTHANAM, Uma , LYGA, John W.
IPC分类号： A61K8/18 , A61Q19/00 , A61K31/165
CPC分类号： A61K8/4926 , A61K8/42 , A61K8/892 , A61K9/0014 , A61K31/165 , A61K31/203 , A61K31/4453 , A61K47/34 , A61K2800/592 , A61K2800/95 , A61Q19/02 , A61K2300/00
摘要： Embodiments of the invention are generally directed to compositions useful for reducing histamine-induced pigmentation in the skin. The composition may further include other depigmenting agents such as nicotinamide and its melanasome transfer-inhibiting derivatives, 3,3'-thiodipropanoic acid and its tyrosinase-inhibiting derivatives, or resorcinol and its tyrosinase-inhibiting derivatives, in a cosmetically acceptable vehicle.
摘要翻译： 本发明的实施方案通常涉及用于减少组胺诱导的皮肤色素沉着的组合物。 在化妆品可接受的载体中，组合物可进一步包含其他脱色剂，例如烟酰胺及其黑素体转移抑制衍生物，3,3'-硫代二丙酸及其酪氨酸酶抑制衍生物或间苯二酚及其抑制酪氨酸酶的衍生物。
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公开(公告)号：EP2969030A1
公开(公告)日：2016-01-20
申请号：EP14778546.3
申请日：2014-02-26
申请人： AVON PRODUCTS, INC.
发明人： SHAH, Arvind N. , SANTHANAM, Uma , YIM, Sunghan
IPC分类号： A61Q19/02
CPC分类号： A61K8/675 , A61K8/06 , A61K8/46 , A61K2800/49 , A61K2800/592 , A61K2800/596 , A61K2800/782 , A61Q19/02 , A61Q19/08
摘要： Embodiments of the invention are generally directed to compositions comprising lightening agents, nicotinamide and 3,3'-thiodipropanoic acid, in a cosmetically acceptable vehicle, articles of manufacture, and methods of use thereof. The compositions and methods of described herein are effective to lighten an area of skin in need of lightening, such as but not limited to, a subject having overall dark complexion, pigmented skin discoloration, freckles, age spots, liver spots, sun damage, tans, pigmented acne marks, scars, pigmented birthmarks, hyperpigmentation, post-inflammatory hyperpigmentation, post-injury hyperpigmentation, melasma, cholasma, after-burn scar, nail stain, yellowing of skin, dark circles under eyes, and the like. The composition may include additional ingredients accordingly for a colored cosmetic, moisturizer, cleanser, toner, and the like.
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公开(公告)号：EP2819752A1
公开(公告)日：2015-01-07
申请号：EP13754739.4
申请日：2013-02-26
申请人： Avon Products, Inc.
发明人： HWANG, Cheng S. , YIM, Sunghan , SANTHANAM, Uma , LYGA, John W.
摘要： The disclosure describes methods for improving the appearance of skin, particularly, treating, ameliorating, preventing, delaying, and/or improving one or more signs of excess accumulation and/or production of subcutaneous fat, such as cellulite, and conditions related thereto, by topically applying compositions comprising Carnitine PalmitoyI Transferase-I (CPT -I) modulators, optionally with other anti- lipid agents. Also described are compositions and methods for treating, preventing and improving the appearance of skin, particularly, treating, preventing, ameliorating, reducing and/or eliminating loss of subcutaneous fat in the skin, wherein the compositions include natural plant constituents that stimulate lipid synthesis.
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