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公开(公告)号：EP3569587A1
公开(公告)日：2019-11-20
申请号：EP19164151.3
申请日：2015-10-21
申请人： AbbVie Inc.
发明人： CARDINAL-DAVID, Benoit , CHAN, Vincent S. , DEMPAH, Kassibla E. , ENRIGHT, Brian P. , HENRY, Rodger F. , HO, Raimundo , HUANG, Ye , HUTERS, Alexander D. , KLIX, Russell C. , KRABBE, Scott W. , Lindenhurst, Illinois 60046 , LAO, Yanbin , LOU, Xiaochun , MACKEY, Sean E. , MATULENKO, Mark A. , MAYER, Peter T. , MILLER, Christopher P. , STAMBULI, James , VOIGHT, Eric A. , WANG, Zhi , ZHANG, Geoff G. , STELLA, Valentino J.
IPC分类号： C07C47/277 , C07C281/02 , C07C309/24 , C07F9/09 , A61K31/661 , A61K31/6615 , A61P25/16
摘要： The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号：EP4186510A1
公开(公告)日：2023-05-31
申请号：EP22204022.2
申请日：2015-10-21
申请人： AbbVie Inc.
发明人： CARDINAL-DAVID, Benoit , CHAN, Vincent S. , DEMPAH, Kassibla E. , ENRIGHT, Brian P. , HENRY, Rodger F. , HO, Raimundo , HUANG, Ye , HUTERS, Alexander D. , KLIX, Russell C. , KRABBE, Scott W. , KYM, Philip R. , LAO, Yanbin , LOU, Xiaochun , MACKEY, Sean E. , MATULENKO, Mark A. , MAYER, Peter T. , MILLER, Christopher P. , STAMBULI, James , VOIGHT, Eric A. , WANG, Zhi , ZHANG, Geoff G. , STELLA, Valentino J.
IPC分类号： A61K31/661 , C07C47/277 , C07C281/02 , C07C309/24 , C07F9/09 , A61K31/6615 , A61P25/16
摘要： The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
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公开(公告)号：EP3209302B1
公开(公告)日：2019-04-24
申请号：EP15791424.3
申请日：2015-10-21
申请人： AbbVie Inc.
发明人： CARDINAL-DAVID, Benoit , CHAN, Vincent S. , DEMPAH, Kassibla E. , ENRIGHT, Brian P. , HENRY, Rodger F. , HO, Raimundo , HUANG, Ye , HUTERS, Alexander D. , KLIX, Russell C. , KRABBE, Scott W. , KYM, Philip R. , LAO, Yanbin , LOU, Xiaochun , MACKEY, Sean E. , MATULENKO, Mark A. , MAYER, Peter T. , MILLER, Christopher P. , STAMBULI, James , VOIGHT, Eric A. , WANG, Zhi , ZHANG, Geoff G. , STELLA, Valentino J.
IPC分类号： A61K31/661 , A61K31/6615 , A61P25/16
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4.发明公开CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE 审中-公开CARBIDOPA和L-DOPA PRODRUGS及其用于治疗帕金森氏病的用途
公开(公告)号：EP3209302A1
公开(公告)日：2017-08-30
申请号：EP15791424.3
申请日：2015-10-21
申请人： AbbVie Inc.
发明人： CARDINAL-DAVID, Benoit , CHAN, Vincent S. , DEMPAH, Kassibla E. , ENRIGHT, Brian P. , HENRY, Rodger F. , HO, Raimundo , HUANG, Ye , HUTERS, Alexander D. , KLIX, Russell C. , KRABBE, Scott W. , KYM, Philip R. , LAO, Yanbin , LOU, Xiaochun , MACKEY, Sean E. , MATULENKO, Mark A. , MAYER, Peter T. , MILLER, Christopher P. , STAMBULI, James , VOIGHT, Eric A. , WANG, Zhi , ZHANG, Geoff G. , STELLA, Valentino J.
IPC分类号： A61K31/661 , A61K31/6615 , A61P25/16
CPC分类号： C07F9/094 , A61K31/661 , A61K31/6615 , A61K45/06 , C07B2200/13 , C07C47/277 , C07C281/02 , C07C309/24 , C07F9/06 , A61K2300/00
摘要： The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.
摘要翻译： （a）卡比多巴前药，（b）包含卡比多巴前药和/或左旋多巴前药的药物组合和组合物，和（c）治疗帕金森氏病和相关病症的方法，其包括施用卡比多巴前药和 左旋多巴前体药物给予帕金森病患者。
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