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公开(公告)号:EP3359540A1
公开(公告)日:2018-08-15
申请号:EP16785568.3
申请日:2016-10-07
申请人: AbbVie S.À.R.L. , Galapagos NV
发明人: AKKARI, Rhalid , ALVEY, Luke Jonathan , BOCK, Xavier Marie , BROWN, Brian S. , CLAES, Pieter Isabelle Roger , COWART, Marlon D. , CONRATH, Katja E. , CYR, Douglas , DE LEMOS, Elsa , DE WILDE, Gert Jules Hector , DESROY, Nicolas , DUTHION, Béranger , GFESSER, Gregory A. , GOSMINI, Romain Luc Marie , HOUSSEMAN, Christopher Gaëtan , JANSEN, Koen Karel , JI, Jianguo , KYM, Philip R. , LEFRANCOIS, Jean-Michel , MAMMOLITI, Oscar , MENET, Christel Jeanne Marie , MERAYO, Nuria Merayo , NEWSOME, Gregory John Robert , PALISSE, Adeline Marie Elise , PATEL, Sachin V. , PIZZONERO, Mathieu Rafaël , SHRESTHA, Anurupa , SWIFT, Elizabeth C. , TSE, Chris , VAN DER PLAS, Steven Emiel , WANG, Xueqing
IPC分类号: C07D471/04 , C07D519/00 , A61K31/437 , A61P11/00 , G01N33/68
CPC分类号: A61K31/4545 , A61K45/06 , C07D471/04 , C07D519/00 , G01N33/5023 , G01N2800/382
摘要: A corrector agent capable of stabilizing a newly synthesized cystic fibrosis transmembrane conductance regulator (CFTR) protein, useful in the treatment of cystic fibrosis.