公开(公告)号：EP1471883B1

公开(公告)日：2005-12-14

申请号：EP03711876.7

申请日：2003-02-07

申请人： Abbott GmbH & Co. KG

发明人： ROSENBERG, Jörg ,  HANTKE, Thomas ,  BREITENBACH, Jörg

IPC分类号： A61K9/00

CPC分类号： A61K9/146 ,  A23L33/15 ,  A23V2002/00 ,  B01J2/00 ,  A23V2200/224 ,  A23V2250/314 ,  A23V2250/54246 ,  A23V2250/211 ,  A23V2250/712 ,  A23V2250/708 ,  A23V2250/5432 ,  A23V2250/612

摘要： The invention relates to a method for producing water dispersible dry powders from hardly soluble compounds, whereby a dispersion is provided, containing the poorly soluble compound in a microdispersed form in a dispersion agent. The dispersion of the poorly soluble compound is concentrated by tangential-filtration and the dispersion agent is removed. The invention also relates to preparations based on said water dispersible dry powders.

公开(公告)号：EP1750669A1

公开(公告)日：2007-02-14

申请号：EP05740745.4

申请日：2005-04-26

申请人： BOEHRINGER INGELHEIM INTERNATIONAL GMBH ,  Abbott GmbH & Co. KG ,  Boehringer Ingelheim Pharma GmbH & Co. KG

发明人： BOCK, Thomas ,  FRIEDL, Thomas ,  HANTKE, Thomas ,  NEUMANN, Jörg ,  ROSENBERG, Jörg

IPC分类号： A61K9/10 ,  A61K9/20 ,  A61K31/155 ,  A61K31/222 ,  A61P9/10 ,  A61P11/06 ,  A61P17/06 ,  A61P19/02 ,  A61P25/08

CPC分类号： A61K31/155 ,  A61K31/222

摘要： The invention relates to a solid pharmaceutical form obtainable by melt extrusion comprising an LTB4 antagonist, which is embedded in a polymer matrix (solid dispersion).

公开(公告)号：EP1471883A2

公开(公告)日：2004-11-03

申请号：EP03711876.7

申请日：2003-02-07

申请人： Abbott GmbH & Co. KG

发明人： ROSENBERG, Jörg ,  HANTKE, Thomas ,  BREITENBACH, Jörg

IPC分类号： A61K9/00

CPC分类号： A61K9/146 ,  A23L33/15 ,  A23V2002/00 ,  B01J2/00 ,  A23V2200/224 ,  A23V2250/314 ,  A23V2250/54246 ,  A23V2250/211 ,  A23V2250/712 ,  A23V2250/708 ,  A23V2250/5432 ,  A23V2250/612

摘要： The invention relates to a method for producing water dispersible dry powders from hardly soluble compounds, whereby a dispersion is provided, containing the poorly soluble compound in a microdispersed form in a dispersion agent. The dispersion of the poorly soluble compound is concentrated by tangential-filtration and the dispersion agent is removed. The invention also relates to preparations based on said water dispersible dry powders.

公开(公告)号：EP1214300B1

公开(公告)日：2003-09-03

申请号：EP00964201.8

申请日：2000-09-19

申请人： ABBOTT GmbH & Co. KG

发明人： HANTKE, Thomas ,  REHBOCK, Bettina ,  ROSENBERG, Jörg ,  BREITENBACH, Jörg

IPC分类号： C07D239/48 ,  C07D251/18 ,  C07D239/50 ,  C07D403/12 ,  C07D521/00 ,  C07D405/14 ,  A61K31/505 ,  A61P35/00

CPC分类号： C07D239/48 ,  A61K9/1635 ,  A61K31/496 ,  A61K31/505 ,  A61K31/53 ,  C07D231/12 ,  C07D233/56 ,  C07D239/50 ,  C07D249/08 ,  C07D251/18 ,  C07D403/12 ,  C07D405/14