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    METHODS FOR THE EARLY DETECTION OF COLORECTAL CANCER
    1.
    发明公开
    METHODS FOR THE EARLY DETECTION OF COLORECTAL CANCER 有权
    早期检测大肠癌的方法

    公开(公告)号：EP3183578A1

    公开(公告)日：2017-06-28

    申请号：EP15757396.5

    申请日：2015-08-21

    申请人： Abbott Laboratories ,  Hvidovre Hospital, University of Copenhagen

    发明人： DAVIS, Gerard J. ,  GAWEL, Susan H. ,  YANG, Xiaoqing ,  NIELSEN, Hans Jørgen ,  CHRISTENSEN, Ib Jarle

    IPC分类号： G01N33/574 ,  C12Q1/68

    摘要： Provided are methods of diagnosing high risk adenomas or colorectal cancer by detecting the presence and/or amount of at least three biomarkers of CRC in a sample from a subject. The methods and biomarkers may be used to develop an accurate prognosis for a patient having CRC or at risk of having CRC or accurately diagnose a subject having or at risk of having CRC. The methods and biomarkers may be used to identify and/or classify a patient as a candidate for further CRC screening and/or CRC treatment therapy.

    摘要翻译： 提供了通过检测来自受试者的样品中CRC的至少三种生物标志物的存在和/或量来诊断高风险腺瘤或结肠直肠癌的方法。 所述方法和生物标志物可用于为患有CRC或处于患CRC的风险的患者或准确诊断患CRC或具有CRC风险的受试者开发准确的预后。 方法和生物标志物可以用于鉴定和/或分类患者作为进一步的CRC筛选和/或CRC治疗疗法的候选者。