公开(公告)号：EP1053239B1

公开(公告)日：2003-01-08

申请号：EP99906996.6

申请日：1999-02-12

申请人： ABBOTT LABORATORIES ,  LIGAND PHARMACEUTICALS INCORPORATED

发明人： COUGHLAN, Michael, J. ,  ELMORE, Steven, W. ,  KORT, Michael, E. ,  KYM, Philip, R. ,  MOORE, Jimmie, L. ,  PRATT, John, K. ,  WANG, Alan, X. ,  EDWARDS, James, P. ,  JONES, Todd, K.

IPC分类号： C07D491/04 ,  A61K31/44 ,  A61K31/505

CPC分类号： C07D491/04

摘要： Compounds having Formula (I), are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.

公开(公告)号：EP1053239A1

公开(公告)日：2000-11-22

申请号：EP99906996.6

申请日：1999-02-12

申请人： ABBOTT LABORATORIES ,  LIGAND PHARMACEUTICALS INCORPORATED

发明人： COUGHLAN, Michael, J. ,  ELMORE, Steven, W. ,  KORT, Michael, E. ,  KYM, Philip, R. ,  MOORE, Jimmie, L. ,  PRATT, John, K. ,  WANG, Alan, X. ,  EDWARDS, James, P. ,  JONES, Todd, K.

IPC分类号： C07D491/04 ,  A61K31/44 ,  A61K31/505

CPC分类号： C07D491/04

摘要： Compounds having Formula (I), are useful for partially or fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.

公开(公告)号：EP1053240B1

公开(公告)日：2003-04-16

申请号：EP99905971.0

申请日：1999-02-15

申请人： Abbott Laboratories ,  LIGAND PHARMACEUTICALS INCORPORATED

发明人： COUGHLAN, Michael, J. ,  KORT, Michael, E. ,  EDWARDS, James, P. ,  JONES, Todd, K.

IPC分类号： C07D491/052 ,  A61K31/44

CPC分类号： C07D491/04

摘要： Compounds having Formula (I) are useful for partially of fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor in a mammal and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.

公开(公告)号：EP1053240A1

公开(公告)日：2000-11-22

申请号：EP99905971.0

申请日：1999-02-15

申请人： Abbott Laboratories ,  LIGAND PHARMACEUTICALS INCORPORATED

发明人： COUGHLAN, Michael, J. ,  KORT, Michael, E. ,  EDWARDS, James, P. ,  JONES, Todd, K.

IPC分类号： C07D491/052 ,  A61K31/44

CPC分类号： C07D491/04

摘要： Compounds having Formula (I) are useful for partially of fully antagonizing, repressing, agonizing, or modulating the glucocorticoid receptor in a mammal and treating immune, autoimmune and inflammatory diseases in a mammal. Also disclosed are pharmaceutical compositions comprising compounds of Formula (I) and methods of inhibiting immune or autoimmune diseases in a mammal.