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    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES
    1.
    发明公开
    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES 审中-公开

    公开(公告)号：EP4043879A1

    公开(公告)日：2022-08-17

    申请号：EP22154958.7

    申请日：2015-09-25

    申请人： Abbott Point Of Care Inc

    发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  LEE-YOW, Niko Daniel ,  BALL, Sheila Diane

    IPC分类号： G01N33/49 ,  B01L3/00

    摘要： The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES
    2.
    发明公开
    SINGLE CHANNEL CARTRIDGE DEVICE FOR COAGULATION ASSAYS IN FLUID SAMPLES 审中-公开
    用于流体样品中混凝测定的单通道筒装置

    公开(公告)号：EP3198271A1

    公开(公告)日：2017-08-02

    申请号：EP15777817.6

    申请日：2015-09-25

    申请人： Abbott Point Of Care, Inc.

    发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  LEE-YOW, Niko Daniel ,  BALL, Sheila Diane

    IPC分类号： G01N33/49 ,  B01L3/00

    CPC分类号： G01N33/86 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L3/502746 ,  B01L2300/0645 ,  B01L2300/0809 ,  B01L2300/0816 ,  B01L2300/0877 ,  B01L2400/0487 ,  B01L2400/0672 ,  B01L2400/0688 ,  G01N27/403 ,  G01N27/4166 ,  G01N33/4905 ,  G01N2333/96463

    摘要： The present invention relates to analytical testing devices comprising a single channel with micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using a single channel with micro-environment sensors in a point of care test cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample and a conduit fluidically connected to the inlet chamber. The conduit includes a sensor chip including a first micro-environment sensor and a second microenvironment sensor, and a fluid lock valve. The sample analysis cartridge further includes a pump configured to push the biological sample over the first micro-environment sensor and the second microenvironment sensor to the fluidic lock valve such that the biological sample is positioned over the first micro-environment sensor and the second micro-environment sensor.

    摘要翻译： 本发明涉及分析测试装置，其包括具有微环境传感器的单通道和用于测定施加到微环境传感器的流体样本中的凝结的方法，并且具体涉及使用具有微环境的单通道执行凝结测定 传感器在点测试盒中。 例如，本发明可以涉及一种样本分析盒，该样本分析盒包括构造成接收生物样本的入口室和流体地连接至入口室的导管。 导管包括传感器芯片和流体锁定阀，传感器芯片包括第一微环境传感器和第二微环境传感器。 所述样本分析盒还包括泵，所述泵被配置为将所述生物样本推过所述第一微环境传感器和所述第二微环境传感器至所述流体锁定阀，使得所述生物样本位于所述第一微环境传感器和所述第二微环境传感器之上， 环境传感器。

    CARTRIDGE DEVICE WITH SEGMENTED FLUIDICS FOR ASSAYING COAGULATION IN FLUID SAMPLES
    3.
    发明公开
    CARTRIDGE DEVICE WITH SEGMENTED FLUIDICS FOR ASSAYING COAGULATION IN FLUID SAMPLES 审中-公开
    具有分段流体的盒装置用于测定流体样品中的混凝

    公开(公告)号：EP3197603A1

    公开(公告)日：2017-08-02

    申请号：EP15781488.0

    申请日：2015-09-25

    申请人： Abbott Point of Care Inc.

    发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  CAMPBELL, John Lewis Emerson ,  ELBUKEN, Caglar ,  BALL, Sheila Diane ,  LIGHTSTONE, Noam Saul

    IPC分类号： B01L3/00

    CPC分类号： G01N33/86 ,  B01L3/5027 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0633 ,  B01L2400/0672 ,  B01L2400/0688 ,  B01L2400/0694 ,  G01N2333/745 ,  G01N2333/974

    摘要： The present invention relates to analytical testing devices comprising segmented fluidics and methods for assaying coagulation in a fluid sample received within the segmented fluidics. For example, the present invention may be directed to sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a first flow restrictor region, a second reagent, and a second sensor region. The sample analysis cartridge further includes a pump configured to independently mix the first segment in the second conduit and the second segment in the third conduit, and independently position the first segment over the first sensor region and position the second segment over the second sensor region.

    摘要翻译： 本发明涉及包括分段流体学的分析测试设备以及用于分析在分段流体学设备内接收的流体样本中的凝结的方法。 例如，本发明可涉及样本分析盒，所述样本分析盒包括入口室，第一导管，第一导管和第二导管，所述第一导管包括构造成将生物样本分成至少第一段和第二段的第一接头，包含第一试剂的第二导管， 区域和第一流体锁定阀，以及第三导管，其包括第一限流器区域，第二试剂和第二传感器区域。 样本分析盒进一步包括泵，该泵构造成独立地混合第二导管中的第一节段和第三导管中的第二节段，并且独立地将第一节段定位在第一传感器区域上并且将第二节段定位在第二传感器区域上。

    CARTRIDGE DEVICE WITH FLUIDIC JUNCTIONS FOR COAGULATION ASSAYS IN FLUID SAMPLES
    7.
    发明公开
    CARTRIDGE DEVICE WITH FLUIDIC JUNCTIONS FOR COAGULATION ASSAYS IN FLUID SAMPLES 审中-公开
    具有流体接头的流体装置用于流体样本中的混凝测定

    公开(公告)号：EP3198270A1

    公开(公告)日：2017-08-02

    申请号：EP15777815.0

    申请日：2015-09-25

    申请人： Abbott Point Of Care, Inc.

    发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  LEE-YOW, Niko Daniel ,  BALL, Sheila Diane ,  CAMPBELL, John Lewis Emerson

    IPC分类号： G01N33/49

    CPC分类号： G01N33/86 ,  B01L3/502715 ,  B01L3/50273 ,  B01L3/502738 ,  B01L2200/10 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2400/0406 ,  B01L2400/0487 ,  B01L2400/0672 ,  B01L2400/0688 ,  B01L2400/0694 ,  G01N27/4166 ,  G01N33/4905 ,  G01N2333/974

    摘要： The present invention relates to analytical testing devices comprising fluidic junctions and methods for assaying coagulation in a fluid sample received within the fluidic junctions. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber, a first conduit comprising a first junction configured to split a biological sample into at least first and second segments, a second conduit comprising a first reagent, a first sensor region, and a first fluidic lock valve, and a third conduit comprising a second reagent, a second sensor region, and a second fluidic lock valve. The sample analysis cartridge further includes a pump configured to push the first segment over the first sensor region to the first fluidic lock valve, and push the second segment over the second sensor region to the second fluidic lock valve.

    摘要翻译： 本发明涉及包含流体接头的分析测试装置和用于测定在流体接头内接收的流体样本中的凝结的方法。 例如，本发明可以涉及一种样本分析盒，该样本分析盒包括入口室，第一导管，第一导管和第二导管，所述第一导管包括被配置为将生物样本分成至少第一段和第二段的第一接头，包含第一试剂的第二导管， 传感器区域和第一流体锁定阀，以及包括第二试剂，第二传感器区域和第二流体锁定阀的第三导管。 样本分析盒还包括泵，该泵构造成将第一区段推过第一传感器区域到达第一流体锁定阀，并且将第二区段推过第二传感器区域到达第二流体锁定阀。