公开(公告)号：EP3198280A1

公开(公告)日：2017-08-02

申请号：EP15778491.9

申请日：2015-09-25

申请人： Abbott Point Of Care, Inc.

发明人： ZHAO, Tian-Xian ,  WONG, Anjulia Chiu-Yuk ,  MARTIN, Glenn Brian ,  DI TULLIO, Katrina Petronilla ,  THIBODEAU, Isabelle Louisette ,  BREEZE, Steven Roy ,  SUTRALA, Smitha RK ,  HONG, Eric ,  BALL, Sheila Diane

IPC分类号： G01N33/86 ,  B01L3/00

CPC分类号： G01N33/86 ,  B01L3/5027 ,  B01L3/502715 ,  B01L2200/04 ,  B01L2200/0605 ,  B01L2200/0684 ,  B01L2200/0689 ,  B01L2200/16 ,  B01L2300/024 ,  B01L2300/027 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/069 ,  B01L2300/0816 ,  B01L2300/0867 ,  B01L2300/161 ,  B01L2400/0472 ,  B01L2400/0481 ,  B01L2400/0487 ,  B01L2400/0688 ,  G01N2333/96463 ,  G01N2333/974

摘要： The present invention relates to analytical testing devices including micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, performing one or more types of coagulation assays using one or more micro-environment sensors in a single point of care combined test cartridge. For example, the present invention may be directed to test sensor including at least one transducer coated with a polymer layer. The polymer layer comprises a thrombin-cleavable peptide with a detectable moiety.

摘要翻译： 本发明涉及分析测试装置，其包括微环境传感器和用于测定施加到微环境传感器的流体样品中的凝结物的方法，并且具体地，使用一个或多个微环境传感器执行一种或多种类型的凝结测定 在单点护理组合测试墨盒。 例如，本发明可以涉及包括涂覆有聚合物层的至少一个换能器的测试传感器。 聚合物层包含具有可检测部分的凝血酶可裂解肽。

公开(公告)号：EP3197602A1

公开(公告)日：2017-08-02

申请号：EP15778152.7

申请日：2015-09-25

申请人： Abbott Point Of Care, Inc.

发明人： DI TULLIO, Katrina Petronilla ,  TAYLOR, Jay Kendall ,  ZHAO, Tian-Xian ,  WONG, Anjulia Chiu-Yuk ,  MARTIN, Glenn Brian ,  THIBODEAU, Isabelle Louisette ,  BREEZE, Steven Roy ,  SUTRALA, Smitha RK ,  HONG, Eric ,  BALL, Sheila Diane

IPC分类号： B01L3/00 ,  G01N33/49

CPC分类号： G01N33/86 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/50273 ,  B01L2200/04 ,  B01L2200/0684 ,  B01L2300/024 ,  B01L2300/027 ,  B01L2300/0636 ,  B01L2300/0645 ,  B01L2300/0663 ,  B01L2300/0672 ,  B01L2300/0809 ,  B01L2300/0816 ,  B01L2400/0481 ,  G01N27/403 ,  G01N27/4166 ,  G01N27/4167 ,  G01N33/4905 ,  G01N2333/96463

摘要： The present invention relates to sample analysis cartridges comprising micro-environment sensors and methods for assaying coagulation in a fluid sample applied to the micro-environment sensors, and in particular, to performing coagulation assays using micro-environment sensors in a point of care sample analysis cartridge. For example, the present invention may be directed to a sample analysis cartridge including an inlet chamber configured to receive a biological sample, and a conduit fluidically connected to the inlet chamber and configured to receive the biological sample from the inlet chamber. The conduit may include a micro-environment prothrombin time (PT) sensor, and a micro-environment activated partial thromboplastin time (aPTT) sensor.

摘要翻译： 本发明涉及包括微环境传感器和用于测定施加到微环境传感器的流体样本中的凝血的方法的样本分析盒，并且具体地涉及使用微观环境传感器在护理点样本分析中执行凝血测定 墨盒。 例如，本发明可涉及样本分析盒，样本分析盒包括被配置为接收生物样本的入口腔室和流体连接到入口腔室并被配置为从入口腔室接收生物样本的导管。 导管可以包括微环境凝血酶原时间（PT）传感器和微环境激活的部分凝血激酶时间（aPTT）传感器。