ACOUSTIC METHOD FOR TRANSDUCTION AND TRANSFECTION

    公开(公告)号:EP4253522A1

    公开(公告)日:2023-10-04

    申请号:EP22305432.1

    申请日:2022-04-01

    IPC分类号: C12M1/42

    摘要: The present invention relates to a method for introducing foreign nucleic acids (3) into cells (2) assisted with acoustophoresis and comprising a step of sweeping acoustic waves frequency from a first frequency f 1 to a second frequency f 2 using a sweep time ranging from 1 ms to 100 ms, f 2 being superior to f 1 . The present invention also relates to a method for performing transduction of cells (2), cells obtained by the method of the invention and an acoustophoresis device (1) for introducing foreign nucleic acids (3) into cells (2) comprising a chamber (11), at least two inlets (121, 122), at least two outlets (131, 132) and at least one acoustic wave generator (14) is configured to sweep the acoustic waves frequency from a first frequency f 1 to a second frequency f 2 using a sweep time ranging from 1 ms to 100 ms, f 2 being superior to f 1 .

    MULTIPLE BLOOD BAG SYSTEM
    9.
    发明公开

    公开(公告)号:EP3452133A1

    公开(公告)日:2019-03-13

    申请号:EP17721668.6

    申请日:2017-05-04

    IPC分类号: A61M1/02 A61M1/36 B01D21/28

    摘要: The present invention relates to a multiple bag system for fractionating blood, said system comprising a fluid collecting bag (B.00) comprising at least one outlet port; at least first and second sampling bags (B.10, B.12), each comprising at least one inlet port and at least one outlet port; and means for transferring fluid from the fluid collecting bag (B.00) to the sampling bags (B.10, B.12); wherein the means for transferring fluid comprises an acoustic sorter (AS0). The present invention also relates to a method for fractionating blood into blood products.