利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

5 条记录 (耗时 0.014 秒)

    Factorial chemical libraries
    3.
    发明公开
    Factorial chemical libraries 失效
    Faktorielle化学书籍Bibliotheken

    公开(公告)号：EP1324045A2

    公开(公告)日：2003-07-02

    申请号：EP03001316.3

    申请日：1993-04-28

    申请人： Affymetrix, Inc. (a Delaware Corporation)

    发明人： Fodor, Stephen P. ,  Stryer, Lubert

    IPC分类号： G01N33/68 ,  G01N33/543 ,  C07K17/00 ,  C12Q1/70 ,  C12Q1/68

    CPC分类号： C40B30/04 ,  B01J2219/00585 ,  B01J2219/00592 ,  B01J2219/00596 ,  B01J2219/00707 ,  C07K1/047 ,  C07K1/06 ,  C12Q1/6811 ,  C12Q1/6874 ,  G01N33/6845

    摘要： A method and library for determining the sequence of monomers in a polymer which is complementary to a receptor. The method provides for formation of pooled (6) and separate (10, 12) products. Separate products are subjected only to subsequent pooled coupling steps. Each pooled product is subsequently divided for formation of pooled and separate products. The resulting polymer library includes groups of polymer products. A first group of products (42) is used to identify the monomer at a first location in a polymer that is complementary to a receptor. A second group of products (44) is used to identify the monomer at a second location in a polymer that is complementary to a receptor.

    摘要翻译： 用于测定与受体互补的聚合物中的单体序列的方法和文库。 该方法提供合并（6）和分离（10,12）产物的形成。 单独的产品仅受到后续的联合耦合步骤的影响。 随后将每个合并产品分开以形成合并和分离的产品。 所得聚合物文库包括聚合物产物组。 第一组产物（42）用于鉴定在与受体互补的聚合物中的第一位置处的单体。 第二组产物（44）用于在与受体互补的聚合物中的第二位置处鉴定单体。