摘要:
Provided is a method of isolating biochemical molecules on a microarray substrate, the method including providing a microarray substrate to which clusters of different kinds of biochemical molecules being classified by individual spot units are attached, the individual spots being regularly arranged thereon; obtaining location information of the individual spot in which a desired cluster among clusters of the biochemical molecules locates; locating an extraction tool for applying energy to isolate the desired cluster according to the location information; and isolating the desired cluster from the microarray substrate by applying energy in a contact or non-contact manner using the extraction tool.
摘要:
Provided is a method of isolating biochemical molecules on a microarray substrate, the method including providing a microarray substrate to which clusters of different kinds of biochemical molecules being classified by individual spot units are attached, the individual spots being regularly arranged thereon; obtaining location information of the individual spot in which a desired cluster among clusters of the biochemical molecules locates; locating an extraction tool for applying energy to isolate the desired cluster according to the location information; and isolating the desired cluster from the microarray substrate by applying energy in a contact or non-contact manner using the extraction tool.
摘要:
Described is a method of screening inorganic materials for catalysis, the method comprising making an array of inorganic materials by delivering a first component of a first inorganic material and a first component of a second inorganic material to first and second regions on a substrate, delivering a second component of the first inorganic material and a second component of the second inorganic material to the first and second regions on the substrate, simultaneously reacting the components to form at least two inorganic materials, and screening the array of inorganic materials in parallel for a chemical property, the chemical property being catalysis.
摘要:
Methods of adhering polymeric materials to a substrate, either directly or through linker molecules, are disclosed. Structures, for example, microstructures, including microwells and arrays of microwells, may be readily formed using the methods. In some embodiments, microstructures formed completely from polymeric materials are provided, making it possible to tailor the chemical and physical properties of the microstructures. For example, microwells having a bottom comprising a polar polymeric material and well sides/top comprising a non-polar polymeric material are provided. Biochemical reagents may be easily delivered to such 'smart wells' because the intrinsic attraction of the well bottom for the reagents and the intrinsic repulsion between the well sides/top combine to direct the reagents to the wells.
摘要:
Giant magnetoresistive cobalt oxide compounds are produced by combinatorial synthesis. Combinatorial synthesis is done by using a substrate having an array of diverse materials thereon prepared by delivering components to predefined regions on a substrate and simultaneously reacting the components to form at least two materials. Other materials that can be prepared using these methods are covalent network solids, ionic solids and molecular solids. Examples are inorganic, organometallic, intermetallic, ceramic organic polymeric and composite materials. Once prepared, these materials can be screened for useful properties such as magnetoresistance. Thus, the present invention provides for the parallel synthesis and analysis of novel material having useful properties.
摘要:
Die Erfindung betrifft eine modular aufgebaute Vorrichtung zur Halterung von Substanzbibliotheken-Trägern und deren Verwendung zum qualitativen und quantitativen Nachweis bestimmter molekularer Zielmoleküle. Insbesondere betrifft die Erfindung eine Vorrichtung (1) zur Halterung eines Substanzbibliotheken-Trägers, die dadurch gekennzeichnet ist , dass zwei miteinander fixierbare Halterelemente (101 und 102) einen Schichtverbund bestehend aus
(i) einem Deckelelement (200), das auf seiner Unterseite eine Detektionsfläche mit einer Substanzbibliothek (201) aufweist und das mindestens im Bereich der Detektionsfläche optisch durchlässig ist, (ii) einem dichtenden und eine umschlossene Aussparung aufwciscndcn Zwischenelement (300) und (iii) einem mindestens im Bereich der Detektionsfläche des Deckelelements optisch durchlässigen Bodenelement (400)
bilden, wodurch eine optisch durchlässige Kammer (500) mit einem Kammerraum entsteht.
摘要:
The invention relates to a modularly structured device for holding substance library carriers and the use of said device for qualitative and quantitative detection of given molecular target molecules. The invention more particularly relates to a device (1) for holding a substance library carrier, which is characterized in that two holder elements that can be fixed to one another (101 and 102) form a layer composite consisting of: (i) a cover element (200) that has a detection surface with a substance library (201) on its lower surface and that is optically transparent at least in the area of the detection surface; (ii) an intermediate sealing element (300) having an enclosed groove and (iii) an optically transparent bottom element in the area of the detection surface of the cover element (400), whereby an optically transparent chamber area is obtained.