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公开(公告)号：EP1340744A2
公开(公告)日：2003-09-03
申请号：EP03011749.3
申请日：1994-10-07
发明人： Dressman, Bruce A. , Fritz, James E. , Hammond, Marlys , Hornback, William J. , Kaldor, Stephen W. , Kalish, Vincent J. , Munroe, John E. , Reich, Siegfried Heinz , Tatlock, John H. , Shepherd, Timothy A. , Rodriguez, Michael J. , Jungheim, Louis N.
IPC分类号： C07D207/16 , A61K31/47 , A61P31/18 , C07D211/60 , C07D215/50 , C07D217/26 , C07D401/06 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62 , C07C323/60 , C07D209/08 , C07D215/48 , C07D217/02 , C07C237/42
CPC分类号： C07D401/06 , C07C237/42 , C07C323/60 , C07D207/16 , C07D209/08 , C07D211/60 , C07D213/40 , C07D215/48 , C07D215/50 , C07D217/02 , C07D217/06 , C07D217/26 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62
摘要： HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
摘要翻译： 可通过化学合成获得的HIV蛋白酶抑制剂抑制或阻断HIV蛋白酶的生物学活性，导致HIV病毒的复制终止。 这些化合物以及含有这些化合物和任选的其它抗病毒剂作为活性成分的药物组合物适用于治疗已知导致AIDS的HIV病毒感染的患者或宿主。
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公开(公告)号：EP1340744B1
公开(公告)日：2007-05-23
申请号：EP03011749.3
申请日：1994-10-07
发明人： Dressman, Bruce A. , Fritz, James E. , Hammond, Marlys , Hornback, William J. , Kaldor, Stephen W. , Kalish, Vincent J. , Munroe, John E. , Reich, Siegfried Heinz , Tatlock, John H. , Shepherd, Timothy A. , Rodriguez, Michael J. , Jungheim, Louis N.
IPC分类号： C07D217/26 , C07D495/04 , C07F9/62 , C07D401/06 , A61K31/47 , A61P31/18
CPC分类号： C07D401/06 , C07C237/42 , C07C323/60 , C07D207/16 , C07D209/08 , C07D211/60 , C07D213/40 , C07D215/48 , C07D215/50 , C07D217/02 , C07D217/06 , C07D217/26 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62
摘要： HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
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公开(公告)号：EP1340744A3
公开(公告)日：2003-12-03
申请号：EP03011749.3
申请日：1994-10-07
发明人： Dressman, Bruce A. , Fritz, James E. , Hammond, Marlys , Hornback, William J. , Kaldor, Stephen W. , Kalish, Vincent J. , Munroe, John E. , Reich, Siegfried Heinz , Tatlock, John H. , Shepherd, Timothy A. , Rodriguez, Michael J. , Jungheim, Louis N.
IPC分类号： C07D217/26 , C07D495/04 , C07F9/62 , C07D401/06 , A61K31/47 , A61P31/18
CPC分类号： C07D401/06 , C07C237/42 , C07C323/60 , C07D207/16 , C07D209/08 , C07D211/60 , C07D213/40 , C07D215/48 , C07D215/50 , C07D217/02 , C07D217/06 , C07D217/26 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62
摘要： HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
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公开(公告)号：EP0889036B1
公开(公告)日：2004-12-29
申请号：EP98113006.5
申请日：1994-10-07
发明人： Dressman, Bruce A. , Fritz, James E. , Hammond, Marlys , Hornback, William J. , Kaldor, Stephen W. , Kalish, Vincent J. , Munroe, John E. , Reich, Siegfried Heinz , Tatlock, John H. , Shepherd, Timothy A. , Rodriguez, Michael J. , Jungheim, Louis N.
IPC分类号： C07D217/26 , C07D495/04 , C07F9/62 , A61K31/47 , C07D207/16 , C07C323/60 , C07D211/60 , C07D401/06 , C07D401/12
CPC分类号： C07D401/06 , C07C237/42 , C07C323/60 , C07D207/16 , C07D209/08 , C07D211/60 , C07D213/40 , C07D215/48 , C07D215/50 , C07D217/02 , C07D217/06 , C07D217/26 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62
摘要： HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
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公开(公告)号：EP0889036A1
公开(公告)日：1999-01-07
申请号：EP98113006.5
申请日：1994-10-07
发明人： Dressman, Bruce A. , Fritz, James E. , Hammond, Marlys , Hornback, William J. , Kaldor, Stephen W. , Kalish, Vincent J. , Munroe, John E. , Reich, Siegfried Heinz , Tatlock, John H. , Shepherd, Timothy A. , Rodriguez, Michael J. , Jungheim, Louis N.
IPC分类号： C07D217/26 , C07D495/04 , C07F9/62 , A61K31/47 , C07D207/16 , C07C323/60 , C07D211/60 , C07D401/06 , C07D401/12
CPC分类号： C07D401/06 , C07C237/42 , C07C323/60 , C07D207/16 , C07D209/08 , C07D211/60 , C07D213/40 , C07D215/48 , C07D215/50 , C07D217/02 , C07D217/06 , C07D217/26 , C07D401/12 , C07D403/14 , C07D409/12 , C07D417/12 , C07D495/04 , C07F9/62
摘要： HIV protease inhibitors, obtainable by chemical synthesis, inhibit or block the biological activity of the HIV protease enzyme, causing the replication of the HIV virus to terminate. These compounds, as well as pharmaceutical compositions that contain these compounds and optionally other anti-viral agents as active ingredients, are suitable for treating patients or hosts infected with the HIV virus, which is known to cause AIDS.
摘要翻译： 可通过化学合成获得的HIV蛋白酶抑制剂抑制或阻断HIV蛋白酶的生物学活性，导致HIV病毒的复制终止。 这些化合物以及含有这些化合物和任选的其它抗病毒剂作为活性成分的药物组合物适用于治疗已知导致AIDS的HIV病毒感染的患者或宿主。
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