公开(公告)号：EP1583967B1

公开(公告)日：2007-06-27

申请号：EP03795968.1

申请日：2003-12-24

申请人： AiCuris GmbH & Co. KG

发明人： BETZ, Ulrich ,  HEWLETT, Guy ,  KLEYMANN, Gerald ,  LAMPE, Thomas ,  LIN, Tse-I ,  NIKOLIC, Susanne ,  REEFSCHLÄGER, Jürgen ,  WUNBERG, Tobias ,  ZIMMERMANN, Holger ,  ZUMPE, Franz ,  BENDER, Wolfgang ,  HENNINGER, Kerstin ,  JENSEN, Axel ,  KELDENICH, Jörg ,  SCHOHE-LOOP, Rudolf

IPC分类号： G01N33/569 ,  A61P31/22

CPC分类号： C07C311/08 ,  C07C275/40 ,  C07D237/04 ,  G01N33/56994 ,  G01N2500/00

摘要： The invention relates to a method for inhibiting the replication of herpes viruses, to methods for identifying compounds that inhibit the replication of herpes viruses with this method, to compounds with activity directed against herpes viruses, to methods for producing these compounds, and to the use thereof for producing medicaments used in the treatment of herpes infections.

公开(公告)号：EP1732901B1

公开(公告)日：2011-11-02

申请号：EP05715944.4

申请日：2005-03-11

申请人： AiCuris GmbH & Co. KG

发明人： ZIMMERMANN, Holger ,  BRÜCKNER, David ,  HEIMBACH, Dirk ,  HENDRIX, Martin ,  HENNINGER, Kerstin ,  HEWLETT, Guy ,  ROSENTRETER, Ulrich ,  KELDENICH, Jörg ,  LANG, Dieter ,  RADTKE, Martin

IPC分类号： C07D233/90 ,  C07D401/12 ,  C07D403/12 ,  A61K31/4164 ,  A61P31/12

CPC分类号： C07D233/90 ,  C07D401/12 ,  C07D403/12 ,  C07D405/12 ,  C07D409/12

摘要： The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.