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1.发明公开BIPHENYL SUBSTITUIERTE SPIROTETRONSÄUREN UND IHRE VERWENDUNG ZUR BEHANDLUNG RETROVIRALER ERKRANKUNGEN 审中-公开联苯取代SPIROTETRONSÄUREN及其用于治疗病毒性疾病RETRO
公开(公告)号：EP2054053A1
公开(公告)日：2009-05-06
申请号：EP07801624.3
申请日：2007-08-13
发明人： HEIMBACH, Dirk , TERSTEEGEN, Adrian , THEDE, Kai , WELKER, Reinhold , FAST, Beate , PAESSENS, Arnold , DITTMER, Frank , SCHOHE-LOOP, Rudolf , HARRENGA, Axel , HILLISCH, Alexander , HENNINGER, Kerstin , HÜBSCH, Walter , BAUSER, Marcus , PAULSEN, Daniela , BIRKMANN, Alexander , BRETSCHNEIDER, Thomas , FISCHER, Reiner , GRESCHAT, Susanne , URBAN, Andreas , WILDUM, Steffen
IPC分类号： A61K31/343 , C07D307/94 , C07D405/12 , C07D407/10 , C07D491/10 , C07D493/10 , C07D495/10
CPC分类号： C07D307/94 , C07D405/12 , C07D407/10 , C07D491/10 , C07D493/10 , C07D495/10
摘要： The present invention relates to novel substituted spirotetronic acids (I) in which R1 and R2, together with the carbon atom to which they are bonded, form a group of the formula (1), (2), (3) or (4), where * is the carbon atom to which R1 and R2 are bonded, to processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular of retroviral disorders, in people and/or animals.
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2.发明授权
公开(公告)号：EP1910330B1
公开(公告)日：2014-07-23
申请号：EP06754657.2
申请日：2006-07-01
IPC分类号： C07D401/12 , C07D409/12 , C07D417/12 , A61K31/40 , A61K31/38
CPC分类号： C07D409/12 , C07D401/12 , C07D417/12
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公开(公告)号：EP1902030B1
公开(公告)日：2012-04-11
申请号：EP06754586.3
申请日：2006-06-27
发明人： SCHOHE-LOOP, Rudolf , ZIMMERMANN, Holger , HENNINGER, Kerstin , LANG, Dieter , THEDE, Kai , FÜRSTNER, Chantal , BRÜCKNER, David
IPC分类号： C07D215/56 , A61K31/47 , A61P31/12
CPC分类号： C07D215/56
摘要： The invention relates to substituted quinolones of formula (I) and to a method for the production thereof as well as to the use thereof in the manufacture of medicaments for the treatment and/or prophylaxis of diseases, more particularly the use thereof as an antiviral agent, in particular against cytomegalo viruses.
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公开(公告)号：EP1991529B1
公开(公告)日：2009-12-09
申请号：EP07722932.6
申请日：2007-02-26
发明人： SVENSTRUP, Niels , ZIMMERMANN, Holger , KARTHAUS, Dagmar , GOELLER, Andreas , HEIMBACH, Dirk , HENNINGER, Kerstin , LANG, Dieter , PAULSEN, Daniela , RIEDL, Bernd , SCHOHE-LOOP, Rudolf , SCHUHMACHER, Joachim , WUNBERG, Tobias
IPC分类号： C07D213/73 , C07D413/04 , A61K31/4439 , A61K31/44 , A61P31/00
CPC分类号： C07D413/04 , C07D213/73
摘要： The invention relates to substituted arylsulfonamides of formula (I) and to processes for preparing them, to their use for producing medicaments for the treatment and/or prophylaxis of diseases, particularly for use as antiviral agents, especially against cytomegaloviruses.
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5.发明授权4-AMINOCARBONYLAMINO-SUBSTITUTIERTE IMIDAZOLVERBINDUNGEN MIT ANTIVIRALER WIRKUNG 有权具有抗病毒效果4-氨基羰基氨基取代的咪唑化合物
公开(公告)号：EP1732901B1
公开(公告)日：2011-11-02
申请号：EP05715944.4
申请日：2005-03-11
发明人： ZIMMERMANN, Holger , BRÜCKNER, David , HEIMBACH, Dirk , HENDRIX, Martin , HENNINGER, Kerstin , HEWLETT, Guy , ROSENTRETER, Ulrich , KELDENICH, Jörg , LANG, Dieter , RADTKE, Martin
IPC分类号： C07D233/90 , C07D401/12 , C07D403/12 , A61K31/4164 , A61P31/12
CPC分类号： C07D233/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
摘要： The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
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6.发明授权SUBSTITUIERTE CHINAZOLINE ALS ANTIVIRALE MITTEL, INSBESONDERE GEGEN CYTOMEGALOVIREN 有权取代Chinazolines作为抗病毒剂，尤其是对抗巨细胞病毒
公开(公告)号：EP1562913B1
公开(公告)日：2011-07-13
申请号：EP03810409.7
申请日：2003-10-25
发明人： WUNBERG, Tobias , BAUMEISTER, Judith , JESKE, Mario , NIKOLIC, Susanne , SÜSSMEIER, Frank , ZIMMERMANN, Holger , GROSSER, Rolf , HENNINGER, Kerstin , HEWLETT, GUY , KELDENICH, Jörg , LANG, Dieter , TSE-I, Lin
IPC分类号： C07D239/74 , A61K31/517 , A61P31/22
CPC分类号： C07D239/74
摘要： The invention relates to substituted quinazolines and to methods for the production thereof, in addition to the use thereof in the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
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公开(公告)号：EP2278965A2
公开(公告)日：2011-02-02
申请号：EP09722891.0
申请日：2009-03-14
发明人： SCHOHE-LOOP, Rudolf , WELKER, Reinhold , PAESSENS, Arnold , BAUSER, Marcus , STOLL, Friedrike , DITTMER, Frank , HENNINGER, Kerstin , PAULSEN, Daniela , LANG, Dieter
IPC分类号： A61K31/4155 , C07D231/10 , A61P31/18
CPC分类号： C07D231/14 , A61K31/4155 , C07D401/06 , C07D403/06 , C07D413/06 , C07D417/06 , C07D451/06 , C07D491/08 , C07D498/08
摘要： The present invention relates to novel substituted pyrazolamides, methods for the production thereof, use thereof for treating and/or preventing diseases, and use thereof for producing pharmaceuticals for treating and/or preventing diseases, particularly retroviral diseases, in humans and/or animals.
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公开(公告)号：EP1994020A2
公开(公告)日：2008-11-26
申请号：EP07711438.7
申请日：2007-02-02
发明人： FUERSTNER, Chantal , THEDE, Kai , ZIMMERMANN, Holger , BRUECKNER, David , HENNINGER, Kerstin , LANG, Dieter , SCHOHE-LOOP, Rudolf
IPC分类号： C07D401/04 , C07D498/04 , C07D471/10 , C07D498/10 , C07D401/14 , A61K31/4709 , A61P31/22
CPC分类号： C07D401/04 , C07D401/14 , C07D471/10
摘要： The invention relates to substituted quinolines, to a method for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially as antiviral agents, especially for controlling cytomegaloviruses.
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公开(公告)号：EP1853582A2
公开(公告)日：2007-11-14
申请号：EP06706932.8
申请日：2006-02-14
发明人： ZIMMERMANN, Holger , BRÜCKNER, David , HENNINGER, Kerstin , ROSENTRETER, Ulrich , HENDRIX, Martin , KELDENICH, Jörg , LANG, Dieter , RADTKE, Martin , PAULSEN, Daniela , KERN, Armin
IPC分类号： C07D401/12 , C07D233/90 , A61K31/4178 , A61K31/4164 , A61P31/12
CPC分类号： C07D233/90 , C07D401/12
摘要： The invention relates to heterocyclylamide-substituted imidazoles and methods for the production of the same, to the use thereof for the treatment and/or prophylaxis of diseases, to the use thereof for the production of medicaments for the treatment and/or prophylaxis of diseases, and especially to the use thereof as antiviral agents, especially against cytomegaloviruses.
摘要翻译： 本发明涉及杂环基酰胺取代的咪唑及其制备方法，其用于治疗和/或预防疾病的用途，其用于制备治疗和/或预防疾病的药物的用途， 并且特别涉及其作为抗病毒剂，尤其是抗巨细胞病毒的用途。
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公开(公告)号：EP1694665A2
公开(公告)日：2006-08-30
申请号：EP04803948.1
申请日：2004-12-16
发明人： THEDE, Kai , WUNBERG, Tobias , LOWINGER, Timothy , KOLETZKI, Diana , URBAN, Andreas , BAUMEISTER, Judith , HENNINGER, Kerstin
IPC分类号： C07D333/00
CPC分类号： C07D409/04 , C07D333/38 , C07D409/12 , C07D409/14 , C07D417/04
摘要： The invention relates to substituted thiophenes, to methods for the production thereof, and to the use of the same for the treatment and/or prophylaxis of diseases, and for producing medicaments for the treatment and/or prophylaxis of diseases, especially for using as antiviral agents, especially against hepatitis C viruses.
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