公开(公告)号：EP2046949B1

公开(公告)日：2014-01-15

申请号：EP07768453.8

申请日：2007-07-12

申请人： Ajinomoto Co., Inc.

发明人： PTITSYN, Leonid Romanovich ,  ALTMAN, Irina Borisovna ,  KOTLIAROVA, Veronika Aleksandrovna ,  MOKHOVA, Olga, Nikolaevna ,  YAMPOLSKAYA, Tatyana Abramovna ,  KOZLOV, Yury Ivanovich ,  TERASHITA, Masaru ,  USUDA, Yoshihiro ,  MATSUI, Kazuhiko

IPC分类号： C12N9/04

CPC分类号： C12P13/08 ,  C12N9/0006 ,  C12P13/04 ,  C12P13/06 ,  C12P13/10 ,  C12P13/14 ,  C12P13/222 ,  C12P13/227 ,  C12P13/24 ,  C12Y101/01002

公开(公告)号：EP2046949A2

公开(公告)日：2009-04-15

申请号：EP07768453.8

申请日：2007-07-12

申请人： Ajinomoto Co., Inc.

发明人： PTITSYN, Leonid Romanovich ,  ALTMAN, Irina Borisovna ,  KOTLIAROVA, Veronika Aleksandrovna ,  MOKHOVA, Olga, Nikolaevna ,  YAMPOLSKAYA, Tatyana Abramovna ,  KOZLOV, Yury Ivanovich ,  TERASHITA, Masaru ,  USUDA, Yoshihiro ,  MATSUI, Kazuhiko

IPC分类号： C12N9/04

CPC分类号： C12P13/08 ,  C12N9/0006 ,  C12P13/04 ,  C12P13/06 ,  C12P13/10 ,  C12P13/14 ,  C12P13/222 ,  C12P13/227 ,  C12P13/24 ,  C12Y101/01002

摘要： A method for producing an L-amino acid is described, for example L-threonine, L-lysine, L-histidine, L-phenylalanine, L-arginine, L-tryptophan, or L-glutamic acid, using a bacterium of the Enterobacteriaceae family, wherein the bacterium has been modified to enhance an activity of a wild-type alcohol dehydrogenase encoded by the adhE gene or a mutant alcohol dehydrogenase which is resistant to aerobic inactivation.