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1.发明公开Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 审中-公开使用人血管生成素-2的特异性结合剂治疗炎性疾病的方法
公开(公告)号：EP1764370A2
公开(公告)日：2007-03-21
申请号：EP06021829.4
申请日：2004-04-08
申请人： Amgen Inc.
CPC分类号： A61K38/16 , A61K38/08 , A61K38/10 , A61K39/3955 , C07K7/06 , C07K7/08 , C07K14/001 , C07K14/515 , C07K16/22 , C07K2317/52 , C07K2319/30 , A61K2300/00
摘要： Disclosed are peptides of Angiopoietin - 2. Also disclosed are peptides comprising the peptides, methods of making such peptides and peptibodies, and methods of treatment using such peptides and peptibodies.
摘要翻译： 公开了促血管生成素-2的肽。还公开了包含所述肽的肽，制备所述肽和肽体的方法，以及使用所述肽和肽体进行治疗的方法。
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公开(公告)号：EP2316845B1
公开(公告)日：2013-01-16
申请号：EP10075639.4
申请日：2002-10-11
申请人： Amgen Inc.
CPC分类号： C07K14/001 , A61K47/68 , C07K7/06 , C07K7/08 , C07K14/00 , C07K16/22 , C07K2317/73 , C07K2317/92 , C07K2319/30 , C07K2319/32
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公开(公告)号：EP2272869A2
公开(公告)日：2011-01-12
申请号：EP10011651.6
申请日：2002-10-11
申请人： Amgen Inc.
IPC分类号： C07K16/00 , C07K16/46 , A61K39/385 , A61K39/395 , C07K16/22 , A61P35/00 , C12N5/20 , G01N33/577 , C12N15/13 , A61K47/48 , G01N33/68
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/56
摘要： Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.
摘要翻译： 公开了结合血管生成素-2的特异性结合剂，例如完全人类抗体。 还公开了抗体的重链片段，轻链片段和CDR，以及制备和使用抗体的方法。
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4.发明公开Specific binding agents of human angiopoietin-2 审中-公开Spezifische Bindungsmittel des menschlichen血管生成素-2
公开(公告)号：EP2157097A1
公开(公告)日：2010-02-24
申请号：EP09011712.8
申请日：2002-10-11
申请人： Amgen, Inc.
CPC分类号： C07K14/001 , A61K47/68 , C07K7/06 , C07K7/08 , C07K14/00 , C07K16/22 , C07K2317/73 , C07K2317/92 , C07K2319/30 , C07K2319/32
摘要： Disclosed are peptides that bind to Ang-2. Also disclosed are peptibodies comprising the peptides, methods of making such peptides and peptibodies , and methods of treatment using such peptides and peptibodies.
摘要翻译： 公开了结合Ang-2的肽。 还公开了包含肽的肽类，制备这些肽和肽类的方法，以及使用这些肽和肽抗体的治疗方法。
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5.发明公开Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 审中-公开使用人血管生成素-2的特异性结合剂治疗炎性疾病的方法
公开(公告)号：EP1777234A3
公开(公告)日：2007-10-10
申请号：EP06021827.8
申请日：2004-04-08
申请人： Amgen Inc.
CPC分类号： A61K38/16 , A61K38/08 , A61K38/10 , A61K39/3955 , C07K7/06 , C07K7/08 , C07K14/001 , C07K14/515 , C07K16/22 , C07K2317/52 , C07K2319/30 , A61K2300/00
摘要： Disclosed are peptides that bind to Angiopoietin - 2. Also disclosed are peptides comprising the peptides, methods of making such peptides and peptibodies, and methods of treatment using such peptides and peptibodies.
摘要翻译： 公开了结合促血管生成素-2的肽。还公开了包含所述肽的肽，制备所述肽和肽体的方法，以及使用所述肽和肽体进行治疗的方法。
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公开(公告)号：EP2316845A1
公开(公告)日：2011-05-04
申请号：EP10075639.4
申请日：2002-10-11
申请人： Amgen Inc.
CPC分类号： C07K14/001 , A61K47/68 , C07K7/06 , C07K7/08 , C07K14/00 , C07K16/22 , C07K2317/73 , C07K2317/92 , C07K2319/30 , C07K2319/32
摘要： Disclosed are peptides that bind to Ang-2. Also disclosed are peptibodies comprising the peptides, methods of making such peptides and peptibodies, and methods of treatment using such peptides and peptibodies.
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7.发明公开
公开(公告)号：EP1767544A3
公开(公告)日：2007-10-10
申请号：EP06021828.6
申请日：2004-04-08
申请人： Amgen Inc.
CPC分类号： A61K38/16 , A61K38/08 , A61K38/10 , A61K39/3955 , C07K7/06 , C07K7/08 , C07K14/001 , C07K14/515 , C07K16/22 , C07K2317/52 , C07K2319/30 , A61K2300/00
摘要： Disclosed are peptides that bind to Angiopoietin - 2. Also disclosed are peptides comprising the peptides, methods of making such peptides and peptibodies, and methods of treatment using such peptides and peptibodies.
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8.发明公开Methods of treatment of inflammatory diseases using specific binding agents of human angiopoietin - 2 审中-公开特异性结合治疗剂使用对人血管生成素-2的炎性疾病的方法
公开(公告)号：EP1767544A2
公开(公告)日：2007-03-28
申请号：EP06021828.6
申请日：2004-04-08
申请人： Amgen Inc.
CPC分类号： A61K38/16 , A61K38/08 , A61K38/10 , A61K39/3955 , C07K7/06 , C07K7/08 , C07K14/001 , C07K14/515 , C07K16/22 , C07K2317/52 , C07K2319/30 , A61K2300/00
摘要： Disclosed are peptides that bind to Angiopoietin - 2. Also disclosed are peptides comprising the peptides, methods of making such peptides and peptibodies, and methods of treatment using such peptides and peptibodies.
摘要翻译： 本发明公开了肽并绑定到血管生成素 - 2.游离缺失所以盘是肽包括肽，使得搜索肽和肽抗体，并使用搜索肽和肽体治疗方法的方法。
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公开(公告)号：EP2272869B1
公开(公告)日：2013-11-20
申请号：EP10011651.6
申请日：2002-10-11
申请人： Amgen Inc.
IPC分类号： C07K16/22 , C07K16/00 , C07K16/46 , A61K39/385 , A61K39/395 , A61P35/00 , C12N5/20 , G01N33/577 , C12N15/13 , A61K47/48 , G01N33/68
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/56
摘要： Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.
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公开(公告)号：EP2272869A3
公开(公告)日：2011-05-11
申请号：EP10011651.6
申请日：2002-10-11
申请人： Amgen Inc.
IPC分类号： C07K16/22 , C07K16/00 , C07K16/46 , A61K39/385 , A61K39/395 , A61P35/00 , C12N5/20 , G01N33/577 , C12N15/13 , A61K47/48 , G01N33/68
CPC分类号： C07K16/22 , A61K2039/505 , C07K2317/21 , C07K2317/56
摘要： Disclosed are specific binding agents, such as fully human antibodies, that bind to angiopoietin-2. Also disclosed are heavy chain fragments, light chain fragments, and CDRs of the antibodies, as well as methods of making and using the antibodies.
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