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1.发明授权QUINOLINES AND QUINAZOLINE ANALOGS AND THEIR USE AS MEDICAMENTS FOR TREATING CANCER 有权喹啉和CHINAZOLINANALOGE及其作为癌症治疗药物
公开(公告)号：EP1827434B1
公开(公告)日：2014-01-15
申请号：EP05848812.3
申请日：2005-11-29
申请人： Amgen Inc.
发明人： KIM, Tae-seong , BELLON, Steven , BOOKER, Shon , D'ANGELO, Noel , DOMINGUEZ, Celia , FELLOWS, Ingrid , LEE, Matthew , LIU, Longbin , RAINBEAU, Elizabeth , SIEGMUND, Aaron, C. , TASKER, Andrew , XI, Ning , CHENG, Yuan
IPC分类号： A61K31/4709 , C07D401/12 , C07D401/14 , A61P35/00
CPC分类号： C07D401/14 , C07D215/233 , C07D401/12 , C07D409/14 , C07D413/12
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2.发明公开QUINOLINES AND QUINAZOLINE ANALOGS AND THEIR USE AS MEDICAMENTS FOR TREATING CANCER 有权喹啉和CHINAZOLINANALOGE及其作为癌症治疗药物
公开(公告)号：EP1827434A2
公开(公告)日：2007-09-05
申请号：EP05848812.3
申请日：2005-11-29
申请人： Amgen Inc.
发明人： KIM, Tae-seong , BELLON, Steven , BOOKER, Shon , D'ANGELO, Noel , DOMINGUEZ, Celia , FELLOWS, Ingrid , LEE, Matthew , LIU, Longbin , RAINBEAU, Elizabeth , SIEGMUND, Aaron, C. , TASKER, Andrew , XI, Ning , CHENG, Yuan
IPC分类号： A61K31/4709 , C07D401/12 , C07D401/14 , A61P35/00
CPC分类号： C07D401/14 , C07D215/233 , C07D401/12 , C07D409/14 , C07D413/12
摘要： Selected compounds of Formula (I) are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases such as cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes. R - X - W - A - Y - R Formula (I) wherein R is X is O, S, NR2 or CR3R4 W is an substituted or unsubstituted aryl or substituted or unsubstituted 5- or 6- membered heteroaryl.
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