公开(公告)号：EP2794663A1

公开(公告)日：2014-10-29

申请号：EP09829936.5

申请日：2009-12-07

申请人： Angiochem Inc.

发明人： CASTAIGNE, Jean-Paul ,  DEMEULE, Michael ,  GAGNON, Catherine ,  LAWRENCE, Betty

IPC分类号： C07K19/00 ,  A61K38/00 ,  A61K38/22 ,  A61K47/48 ,  C07K14/81 ,  C07K7/08 ,  C12N15/62 ,  C07K14/575

CPC分类号： A61K47/48246 ,  A61K38/00 ,  A61K38/2264 ,  A61K38/2278 ,  A61K47/64 ,  C07K7/08 ,  C07K14/001 ,  C07K14/57563 ,  C07K14/5759 ,  C07K14/8117 ,  C07K2319/00

摘要： The present invention features a compound having the formula A-X-B, where A is peptide vector capable of enhancing transport of the compound across the blood- brain barrier or into particular cell types, X is a linker, and B is a peptide therapeutic. The compounds of the invention can be used to treat any disease for which the peptide therapeutic is useful.