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1.发明公开COMPOSITION COMPRISING MELISSA LEAF EXTRACT FOR ANTI-ANGIOGENIC AND MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY 有权MELISSA叶提取物含有抗血管生成效力的组成和MATRIXMETALLOPROTEINASEHEMMENDER
公开(公告)号：EP1349558A1
公开(公告)日：2003-10-08
申请号：EP01270341.9
申请日：2001-12-12
申请人： Angiolab, Inc. , Kim, Min-Young
IPC分类号： A61K35/78
CPC分类号： A61K36/31 , A23L33/105 , A61K8/97 , A61K36/53 , A61K45/06 , A61K2800/782 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： The present invention relates to a composition comprising Melissaleaf extract that inhibits angiogenesis and matrix metalloproteinase activity. The Melissa leaf extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, sothat it can be applied to treat or prevent diseases related to angiogenesis and matrix metalloproteinase. The compositin of the present invention comprising Melissa leaf extract may also comprise more than one component of the other anti-angiogenic, anti-cancer, anti-inflammatory and anti-aging components. This particular composition comprising Melissa leaf extract can be used for pharmaceutical, dietetic and/or cosmetic purposes.
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2.发明授权COMPOSITION COMPRISING MELISSA LEAF EXTRACT FOR ANTI-ANGIOGENIC AND MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY 有权MELISSA叶提取物含有抗血管生成效力的组成和MATRIXMETALLOPROTEINASEHEMMENDER
公开(公告)号：EP1349558B1
公开(公告)日：2011-06-15
申请号：EP01270341.9
申请日：2001-12-12
申请人： Angiolab, Inc. , Kim, Min-Young
CPC分类号： A61K36/31 , A23L33/105 , A61K8/97 , A61K36/53 , A61K45/06 , A61K2800/782 , A61Q19/00 , A61Q19/08 , A61K2300/00
摘要： The present invention relates to a composition comprising Melissaleaf extract that inhibits angiogenesis and matrix metalloproteinase activity. The Melissa leaf extract of the present invention inhibits angiogenesis and activity of matrix metalloproteinase, sothat it can be applied to treat or prevent diseases related to angiogenesis and matrix metalloproteinase. The compositin of the present invention comprising Melissa leaf extract may also comprise more than one component of the other anti-angiogenic, anti-cancer, anti-inflammatory and anti-aging components. This particular composition comprising Melissa leaf extract can be used for pharmaceutical, dietetic and/or cosmetic purposes.
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3.发明公开PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY 有权与查尔酮或其衍生物FOR基质金属蛋白酶的抗炎作用的药物组合物
公开(公告)号：EP1450777A1
公开(公告)日：2004-09-01
申请号：EP02802394.3
申请日：2002-10-31
申请人： Angiolab Inc.
IPC分类号： A61K31/03
摘要： The present invention provides an MMP-inhibitory composition comprising chalcone or its derivatives. They inhibit the MMPs in collagenase subfamily as well as those in gelatinase subfamily. The MMP inhibitory activity of chalcone derivatives was similar to or greater than that of parent compound, chalcone. Chalcone or its derivatives of the present invention inhibit activity of matrix metalloproteinase, so that it can be applied to treat and prevent diseases related to matrix metalloproteinase.
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4.发明授权PHARMACEUTICAL COMPOSITION CONTAINING CHALCONE OR ITS DERIVATIVES FOR MATRIX METALLOPROTEINASE INHIBITORY ACTIVITY 有权与查尔酮或其衍生物FOR基质金属蛋白酶的抗炎作用的药物组合物
公开(公告)号：EP1450777B1
公开(公告)日：2013-05-08
申请号：EP02802394.3
申请日：2002-10-31
申请人： Angiolab Inc.
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