公开(公告)号：EP1701742A2

公开(公告)日：2006-09-20

申请号：EP04806240.0

申请日：2004-12-23

申请人： Archimedes Development Limited

发明人： CASTILE, J. D., West Pharm. Research Centre Ltd. ,  CHENG, Y.-H., West Pharm. Research Centre Ltd. ,  JENKINS, P. G., West Pharm. Research Centre Ltd. ,  SMITH, Alan, West Pharm. Research Centre Ltd. ,  WATTS, P. J., West Pharm. Research Centre Ltd.

IPC分类号： A61K47/40 ,  A61K47/36 ,  A61K9/16

CPC分类号： B82Y5/00 ,  A61K9/0043 ,  A61K9/1623 ,  A61K9/1652 ,  A61K31/4184 ,  A61K47/36 ,  A61K47/40 ,  A61K47/6951 ,  Y10S514/923

摘要： The present invention provides compositions for the intranasal administration of zolpidem or a pharmaceutically acceptable salt thereof. Preferred compositions of the invention are in the form of aqueous solutions. Optionally the compositions of the invention comprise a cyclodextrin and/or chitosan, a salt or derivative thereof or a salt of a derivative of chitosan. The compositions can be used for the treatment or prevention insomnia or the treatment of neurological disorders such as those arising from brain trauma, stroke and spinocerebellar ataxia or in the treatment of Parkinson's disease.