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1.发明授权S-triazolyl alpha-mercaptoacetanilides as inhibitors of HIV reverse transcriptase 有权S-三唑基的αMercaptoacetanilide作为HIV逆转录酶抑制剂
公开(公告)号：EP2402011B1
公开(公告)日：2012-11-14
申请号：EP11177941.9
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： The invention relates to a compound represented by the formula: and a compound represented by the formula: These compounds are useful intermediates in the synthesis of ±-triazolyl a-mercaptoacetanilides as inhibitors of HIV reverses transcriptase.
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2.发明授权S-triazolyl alpha -mercaptoacetanilides as inhibitors of HIV reverse transcriptase 有权S-三唑基的α-Mercaptoacetanilide作为HIV逆转录酶抑制剂
公开(公告)号：EP2135608B1
公开(公告)日：2011-10-12
申请号：EP09170772.9
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： The invention relates to a compound represented by the formula: and a compound represented by the formula: These compounds are useful intermediates in the synthesis of ±-triazolyl a-mercaptoacetanilides as inhibitors of HIV reverses transcriptase.
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3.发明公开Triazolyl alpha -mercaptoacetanilides as inhibitors of HIV reverse transcriptase 审中-公开三唑基α巯基乙酰替苯胺甲型肝炎逆转转录酶von HIV
公开(公告)号：EP2609917A1
公开(公告)日：2013-07-03
申请号：EP12187096.8
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo , De La Rosa, Martha , Gunic, Esmir , Hong, Zhi , Lang, Stanley , Kim, Hong, Woo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： A series of S-triazolyl α-mercaptoacetanilides having general structure (I) are provided, where Q is CO 2 H, CONR 2 , SO 3 H,or SO 2 NR 2 . The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
摘要翻译： 提供了具有通式（I）的一系列S-三唑基±巯基乙酰替苯胺，其中Q是CO 2 H，CONR 2，SO 3 H或SO 2 NR 2。 该化合物抑制HIV的逆转录酶的几种变体，并且可用于治疗HIV感染。
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4.发明授权S-triazolyl alpha -mercaptoacetanilides as inhibitors of HIV reverse transcriptase 有权S-三唑基的α-Mercaptoacetanilide作为HIV逆转录酶抑制剂
公开(公告)号：EP2135608B8
公开(公告)日：2012-03-21
申请号：EP09170772.9
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： The invention relates to a compound represented by the formula: and a compound represented by the formula: These compounds are useful intermediates in the synthesis of ±-triazolyl a-mercaptoacetanilides as inhibitors of HIV reverses transcriptase.
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5.发明公开Triazolyl alpha -mercaptoacetanildes as inhibitors of HIV reverse transcriptase 审中-公开三唑基α巯基乙酰替苯胺甲型肝炎逆转转录酶von HIV
公开(公告)号：EP2433633A1
公开(公告)日：2012-03-28
申请号：EP11184025.2
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo , De La Rosa, Martha , Gunic, Esmir , Hong, Zhi , Lang, Stanley , Kim, Hong, Woo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： A series of triazolyl α-mercaptoacetanilides having general structure are provided, where Q is CO 2 H, CONR 2 , SO 3 H, or SO 2 NR 2 . The compounds inhibit several variants of the reverse transcriptase of HIV, and are useful in the treatment of HIV infections.
W=S,O,N摘要翻译： 提供一系列具有一般结构的三唑基± - 巯基乙酰替苯胺，其中Q为CO 2 H，CONR 2，SO 3 H或SO 2 NR 2。 该化合物抑制HIV的逆转录酶的几种变体，并且可用于治疗HIV感染。 W = S，O，N
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6.发明公开
公开(公告)号：EP2402011A1
公开(公告)日：2012-01-04
申请号：EP11177941.9
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： The invention relates to a compound represented by the formula:
and a compound represented by the formula:
These compounds are useful intermediates in the synthesis of α-triazol amercaptoacetanilides as inhibitors of HIV reverse transcriptase.摘要翻译： 本发明涉及由下式表示的化合物和由下式表示的化合物：这些化合物是合成作为HIV逆转录酶抑制剂的±三唑阿魏酸乙酰替苯胺的有用中间体。
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7.发明公开S-triazolyl alpha -mercaptoacetanilides as inhibitors of HIV reverse transcriptase 有权S-三唑基-α-巯基乙酰苯胺抑制剂HIV-Umkehr转录酶
公开(公告)号：EP2135608A1
公开(公告)日：2009-12-23
申请号：EP09170772.9
申请日：2005-08-25
发明人： Girardet, Jean-Luc , Koh, Yung-Hyo , De La Rosa, Martha , Gunic, Esmir , Hong, Zhi , Lang, Stanley , Kim Hong, Woo
IPC分类号： A61K31/4196 , C07D249/08 , A61P31/18
CPC分类号： C07D249/12 , C07D249/14 , C07D401/04 , C07D401/12 , C07D405/12
摘要： The invention relates to a compound represented by the formula:
and a compound represented by the formula:
These compounds are useful intermediates in the synthesis of α-triazolyl a-mercaptoacetanilides as inhibitors of HIV reverses transcriptase.摘要翻译： 本发明涉及由下式表示的化合物和由下式表示的化合物：这些化合物是合成α-三唑基α-巯基乙酰替苯胺作为HIV逆转录酶抑制剂的有用中间体。
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