公开(公告)号：EP3370791A1

公开(公告)日：2018-09-12

申请号：EP16805222.3

申请日：2016-11-03

申请人： Ariel-University Research and Development Company Ltd.

发明人： BARANES, Danny ,  WEISS, Orly Eva ,  CHANJI, Eyal ,  MORAD, Tzachy ,  HAMMER, Liat ,  MERFELD, Ido

IPC分类号： A61L27/36 ,  A61L27/38 ,  A61L27/44 ,  A61L27/46 ,  A61L27/54

CPC分类号： A61L27/46 ,  A61L27/3616 ,  A61L27/3675 ,  A61L27/38 ,  A61L27/446 ,  A61L27/54 ,  A61L2300/414 ,  A61L2300/426 ,  A61L2300/43 ,  A61L2430/32

摘要： Methods and compositions for repair and regeneration of neural tissue are provided. Particularly, methods and compositions for promoting neural tissue wound healing and treatment of traumatic brain injury using porous crystalline calcium carbonate particles and a biocompatible polymer, for example compositions comprising porous coral exoskeleton particles in combination with a biocompatible polymer, and optionally comprising neural growth agents and platelets for application to damaged neural tissue for enhancing neural regrowth and recovered functionality, in, for example, but not limited to, traumatic brain injury (TBI).